K562细胞作为体外研究白血病细胞增殖与分化的良好模型,其转录因子及作用机制研究是一关键的环节。本文就其中GATA、STAT、Sp家族等在K562细胞增殖分化中的作用及其相关进展作一综述。
Leukemic cell line K562 is a good model to investigate proliferation and differentiation of leukemic cell. Mechanism of transcription factor is a key link of the investigation. In this paper, the progress and role of GATA, STAT in proliferation and differentiation ofK562 were reviewed.