黄曲霉可以引起粮油作物的霉变,其产生的毒素能够污染粮食及其制品,对人类和动物的健康造成极其严重的危害。本文概述了黄曲霉毒素在产生、运输和调控阶段的分子生物学过程,重点对黄曲霉毒素污染控制方法,如:遗传育种法、物理降解法及化学降解法等进行综述,并对植物源杀菌剂控制前期毒素污染,以及干预吸收控制后期毒素污染的前景进行展望。
Aspergillus flavus can contaminate crops and food products, and produce aflatoxins which cause extremely serious damage to human and animal health. In this study, the molecular mechanisms involving aflatoxins biosynthesis, regulation and transport are reviewed. The existing strategies used to control aflatoxin contamination, such as genetic engineering and breeding, and physical and chemical decomposition are summarized. Additionally, the development and application of botanical fungicides and biological interventions are also highlighted and discussed.