中文摘要：

为了研制高效、安全、无污染的抗生素替代物作为断奶仔猪饲料添加剂，本研究观察了中药超微粉对21日龄断奶仔猪外周血白细胞分类和血清抗氧化功能的影响。结果表明，D7时，超微粉组MDA含量显著小于抗生素组和对照组（P〈0．05），NO含量显著小于对照组（P〈0．05）；D14时，超微粉组NO含量显著大于抗生素组和对照组（P〈0．05）；D28时，超微粉组NEU计数和百分率及MON百分率均显著小于、LYM百分率显著大于对照组（P〈0．05），N／L小于抗生素组（P〉0．05）、显著小于对照组（P〈0．05），SOD活性显著大于抗生素组和对照组（P〈0．05），GSH活性显著大于对照组（P〈0．05）。上述指标的变化，与该超微粉对断奶仔猪的防病促生长作用有一定联系。

英文摘要：

The experiment was conducted to determine the effects of Chinese herbal ultra-fine powder with average granule diameter of 30 μm as dietary additive on blood total and differential counts of leucocytes and serum anti-oxidative status in piglets weaned at 21 day old in order to study and develop a novel antibiotic candidate with strong efficacy and perfect safety. The data showed that the ultra-fine powder decreased the content of MDA compared with the other two groups （ P 〈 0.05 ）, and of NO compared with that of the supplement-free group （ P 〈 0.05 ） on day 7 after the initiation of supplement. On day 14,the content of NO in the power group was higher than that of the other two groups （ P 〈 0.05 ）. On day 28 ,the powder decreased the numbers of NEU and ratio of NEU and MON （ P 〈 0.05 ）, and increased the ratio of LYM compared with the supplement-free groups （ P 〈 0.05 ） ; the power decreased the N-L ratio compared with the supplement-free （P 〉 0.05 ） and colistin groups （P 〈0.05 ） and increased the activity of SOD compared with the other two groups （ P 〈 0.05 ） and of GSH compared with the supplement-free group （ P 〈 0.05 ）. These results suggested that the regulation actions of the Chinese herbal ultra-fine powder to the above-mentioned parameters might be contributed to its functions of preventing disease and promoting growth to the early-weaned piglets.