研究了在室温下ZnCl2催化硒酚对环氧化合物开环反应合成β-羟基硒醚.通过这一简单、有效和原子经济性的反应,高收率和高选择性地合成了几种β-羟基硒醚.从环氧化合物3-邻甲苯氧基-1,2-环氧丙烷出发,经一锅三步反应,合成了相应的1,3-噁唑-2-酮.
ZnCl2-catalyzed selenolysis of epoxides with ArSeH was investigated in ethanol at room temperature. A variety of β-hydroxyl selenides were obtained in excellent yield and good regioselectivity by the simple, efficient and atomic economic procedure. Starting from epoxide o-cresyl glycidyl ether, a one-pot three-step procedure was used for the chemoselective synthesis of N-tosyl-1,3-oxazolidin-2-ones.