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中文摘要：
吖啶酮生物碱是一类重要的生物活性物质，芸香科柑橘类植物是天然吖啶酮的主要来源。至今已从柑橘类植物中分离得到20多种吖啶酮生物碱，它们在抗癌、抗肿瘤、抗病毒、抗疟疾和抗白血病等方面有重要作用。我国柑橘资源丰富．利用我国乃至世界丰富的柑橘资源对柑橘吖啶酮的开发利用前景广阔。对柑橘吖啶酮的已有研究多以根茎为实验材料，关于果实中吖啶酮的研究尚无报道。阐述了柑橘吖啶酮的结构特点、生理活性、生物合成和研究进展情况。并提出了植物天然吖啶酮的研究现状和形势。同时指明了在柑橘吖啶酮研究领域存在的问题及今后在此领域的研究重点和方向。
英文摘要：
Acridone alkaloids, a group of important bioactive compounds, are mainly in the citrus plant of Rutaceac family. So far, more than 20 natural acridone alkaloids have been isolated from the citrus plant, and they are known to have various functions and bioactivities such as anticancer, antitumour, antivirus, antiproliferation and anti-malaria. Current study of citrus acridone is focusing on the tissue of root and stem, and there is no report on the study of fruit acridone up to now. The structure, physiological bioactivities, and biosynthesis of citrus acridone alkaloids are reviewed in the present article. The current problem and the emphases of the future work in this field are also discussed.
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