中文摘要：

目的 研究60名中国健康成人鼻腔气流动力学特征,建立健康人鼻腔气流特征值数据库.方法 采用计算流体力学方法,分析鼻腔流场特征及鼻腔总鼻阻力、最大流速、最大壁剪切力、鼻腔黏膜面积、鼻腔容积、黏膜面积-容积比等气流动力学指标.使用SPSS 16.0软件进行统计学分析.结果 气流主要流经总鼻道且流线分布均匀,鼻阻力平均值为（0.211±0.085）kPa· s·L-1,最大流速（12.01±2.79）m/s,最大黏膜剪切力（2.50±0.89） Pa,鼻腔黏膜面积（161.2±34.7）mm2,鼻腔容积（31.7±8.1）ml,黏膜面积-容积比（0.58±0.09）mm-1.气流特征值间无明显性别差异.结论 鼻腔气流主要流经总鼻道,鼻阈区为主要阻力平面.气流特征无性别差异.健康人鼻腔气流动力学特征值与鼻腔流场分布特征数据库的建立为进行鼻腔数值模拟研究奠定基础.

英文摘要：

Objectives To investigate the aerodynamics characteristics of nasal cavity in inspiration phase from 60 healthy Chinese people and provide the reference values for future computational fluid dynamics （CFD） research.Methods CFD was used for numerical simulation.The indices of main airflow passage,total nasal airway resistance,maximal velocity,maximal wall shear stress,nasal mucosa area,nasal volume and surface area-to-volume ratio were extracted from CFD analysis results.SPSS 16.0 softwarewas used to analyze the data.Results The main airflow passage in nasal cavity was common meatus,the mean total nasal airway resistance was （0.211 ± 0.085） kPa · s · L-1,the mean maximal velocity was （12.01 ± 2.79） m/s,the mean maximal wall shear stress was （2.50 ± 0.89） Pa,the mean nasal mucosa area was （161.2± 34.7） mm2,the mean nasal volume was （31.7 ± 8.1） ml and the mean surface area-to-volume ratio was （0.58 ±0.09） mm-1.No significant difference was detected in aerodynamics indices between male and female people.Conclusions The main airflow passage is located in common meatus.The nasal valve area is the key constrictive plane in nasal cavity.There are no gender differences of main airflow characteristics in nasal cavity.The normal ranges of aerodynamics indices could be used for reference values for future CFD research.