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Cyclic mechanical stretch regulates MMPs and TIMPs expression in corneal fibroblasts
  • ISSN号:1004-7220
  • 期刊名称:《医用生物力学》
  • 时间:0
  • 分类:R312[医药卫生—基础医学]
  • 作者机构:[1]Institute of Applied Mechanics and Biomedical Engineering,Taiyuan University of Technology
  • 相关基金:supported by the National Natural Science Foundation of China(11032008);Natural Science Foundation of Shanxi Province(2012011046-2)
中文摘要:

Laser in situ keratomileusis(LASIK)is a relatively new ophthalmic procedure in refractive surgery.It involves the use of a microkeratome to create a thin corneal flap followed by excimer laser ablation of the corneal stroma and repositioning of the flap.However,complications are bound to occur when a surgical procedure is performed with increasing frequency.In some cases,serious complications such as keratectasia occurred.Risk factors for corneal keratectasia include a thin cornea at baseline,thick corneal flap,excessive ablation,irregular corneal thickness,diverse ablation rates,preexisting keratoconus or form fruste keratoconus,and high intraocular pressure(IOP)~[1].It is evident from incisional refractive surgery that the cornea is not mechanically inert.The mechanical environment of the central corneal tissue is also altered un-

英文摘要:

Laser in situ keratomileusis(LASIK)is a relatively new ophthalmic procedure in refractive surgery.It involves the use of a microkeratome to create a thin corneal flap followed by excimer laser ablation of the corneal stroma and repositioning of the flap.However,complications are bound to occur when a surgical procedure is performed with increasing frequency.In some cases,serious complications such as keratectasia occurred.Risk factors for corneal keratectasia include a thin cornea at baseline,thick corneal flap,excessive ablation,irregular corneal thickness,diverse ablation rates,preexisting keratoconus or form fruste keratoconus,and high intraocular pressure(IOP)~[1].It is evident from incisional refractive surgery that the cornea is not mechanically inert.The mechanical environment of the central corneal tissue is also altered un-

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期刊信息
  • 《医用生物力学》
  • 北大核心期刊(2011版)
  • 主管单位:教育部
  • 主办单位:上海交通大学
  • 主编:戴尅戎
  • 地址:上海市制造局路639号
  • 邮编:200011
  • 邮箱:shengwulixue@163.com
  • 电话:021-53315397
  • 国际标准刊号:ISSN:1004-7220
  • 国内统一刊号:ISSN:31-1624/R
  • 邮发代号:4-633
  • 获奖情况:
  • 国内外数据库收录:
  • 俄罗斯文摘杂志,美国化学文摘(网络版),英国农业与生物科学研究中心文摘,波兰哥白尼索引,荷兰文摘与引文数据库,美国剑桥科学文摘,中国中国科技核心期刊,中国北大核心期刊(2011版),中国北大核心期刊(2014版)
  • 被引量:4565