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中文摘要：
鼓膜穿孔是一种非常普遍的中耳疾病，其对人中耳传声的影响并没有得到很全面的研究。本文根据健康志愿者（右耳）完整的CT数据，建立了包括外耳道、鼓膜、听骨链、中耳韧带／肌肉、中耳腔以及内耳液体在内的有限元模型，真实完整地再现了其复杂结构及边界约束。利用模型进行了外耳、中耳和内耳的声固耦合分析，研究了鼓膜穿孔位置和穿孔大小对中耳传声的影响。研究结果表明了本文建立的三维有限元模型对研究鼓膜穿孔对中耳系统传声的影响是可行的。
英文摘要：
Tympanic membrane perforations are common sequelae of middle ear disease. Sound transmission through middle ears with tympanic membrane perforations is not well understood. In this study, a three-dimensional finite element model of human ear with perforations is proposed that includes the ear canal, tympanic membrane, ossicular bones, middle ear suspensory ligaments/muscles, middle ear cavity, and inner ear fluid. The acoustic-structural coupling effect of the canal, tympanic membrane and the middle ear cavity is conducted and employed to predict the effects of perforation location and perforation size on sound transmission of the middle ear. The results show that the finite element model with perforations may be useful to predict the conductive hearing loss resulting from a tympanic membrane perforation.
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