对四数九里香的地上部位进行了化学成分研究。运用硅胶和Sephadex LH-20柱色谱及制备HPLC和TLC等多种分离方法进行分离纯化,共分离得到9个化学成分,通过NMR和MS数据分析,并结合文献对比,鉴定其结构分别为3,3'-[oxybis(methylene)]bis(9-methoxy-9H-carbazole)(1),murrastifoline B(2),murrayaquinone A(3),2,4-二甲氧基苯酚(4),1,2-二甲氧基-4-硝基苯(5),间甲基苯甲醚(6),丁香树脂酚葡萄糖苷(7),β-谷甾醇(8),3-甲氧基-4-羟基反式苯丙烯酸正十八醇酯(9)。化合物4–6和9为首次从九里香属植物中分离得到,化合物2–9为该种植物中首次分离得到。
The aim of this study is to perform a phytochemical investigation of the aerial parts of Murraya tetramera Huang. Nine compounds were isolated by silica gel and Sephadex LH-20 chromatography, together with preparative TLC and HPLC methods. By analysis of the MS and NMR spectroscopic data and comparison with those in literature, these nine compounds were identified as 3,3'-[oxybis(methylene)]bis(9-methoxy-9H-carbazole)(1), murrastifoline B(2), murrayaquinone A(3), 2,4-dimethoxyphenol(4), 1,2-dimethoxy-4-nitrobenzene(5), 3-methylanisole(6),(–)-syringaresinol-4-O-β-D-glucopyranoside(7), β-sitosterol(8), and octadecanyl-3-methoxy-4-hydroxylbenzeneacrylate(9), respectively. Among them, compounds 4–6 and 9 were described from the genus Murraya for the first time, and compounds 2–9 were isolated from M. tetramera for the first time.