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青风藤中菲、蒽醌及酚类成分的研究(英文)
  • ISSN号：1003-1057
  • 期刊名称：《中国药学：英文版》
  • 时间：0
  • 分类：R284.1[医药卫生—中药学;医药卫生—中医学]
  • 作者机构：北京大学医学部药学院天然药物及仿生药物国家重点实验室
  • 相关基金：National Natural Sciences Foundation of Chin(NS FC;Grant Nos.81222051 and 81473106);National Key Technology R&D; Program“New Drug Innovation”of China(Gran No s.2012ZX09301002-002-002 and 2012ZX09304-005)
作者： 吕海宁, 赵明波, 姜勇, 屠鹏飞
关键词： 青风藤, 菲, 蒽醌, 酚类成分
中文摘要：

本研究运用硅胶和Sephadex LH-20柱色谱及制备HPLC等多种分离方法对传统中药青风藤进行了化学成分研究工作,共分离得到19个化合物,通过NMR和MS数据分析,并结合文献对比,鉴定了它们的结构,包括3个菲、6个蒽醌和10个酚类成分。其中化合物1和2为两个新天然产物。借助2D NMR技术对化合物1的波谱数据进行了首次全归属,化合物2的波谱数据为首次报道。化合物1–19均首次从本属植物中分离得到,其中菲类及蒽醌类结构为该属植物中首次报道的化合物类型。

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期刊信息
  • 《中国药学：英文版》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:北京大学药学院
  • 主编：王夔
  • 地址：北京市学院路38号
  • 邮编：100083
  • 邮箱：zggy@mail.bjmu.edu.cn
  • 电话：010-82801713
  • 国际标准刊号：ISSN：1003-1057
  • 国内统一刊号：ISSN：11-2863/R
  • 邮发代号:
  • 获奖情况:
  • 国内外数据库收录:
  • 被引量:708