欢迎您！东篱公司
退出
-
申报数据库
-
立项数据库
-
成果数据库
-
项目获奖数据库
中文摘要：
为寻找新型昆虫生长调节活性化合物，设计合成了15个未见文献报道的5-芳甲氧基取代的3（2H）-哒嗪酮衍生物，所有化合物结构均通过^1H NMR，IR和元素分析确证．初步生物活性研究表明，化合物80对2龄家蝇幼虫有明显的抑制作用；化合物8a，8c，8g和8j对3龄蝗蝻显示出较好的生物活性．对目标化合物的构效关系亦进行了初步探讨．
英文摘要：
In order to search for new insect growth regulators, fifteen new compounds containing 5-oxo- 3（2H）-pyridazinone derivatives were designed and synthesized. Their structures were confirmed by ^1H NMR, IR spectra and elemental analysis. In the preliminary bioassay test, compound 8o obviously disrupted the development of second-instar housefly larvae. Compounds 8a, 8c, 8g and 8j also showed good activity against the third-instar nymphs of locusts （Locusta migratoria manilensis）. The structure-activity relation- ship of compounds was also discussed.
同期刊论文项目
同项目期刊论文
期刊信息
位置：