疱疹单一的病毒(HSV ) 是有二 serotypes HSV-1 和 HSV-2 的一组普通人的病原体。HSV 的流行是世界范围的。它首先通过上皮的房间感染人,当它介绍潜伏的感染进神经系统时。在病毒的潜伏期间,仅仅作为联系潜伏的抄本(LAT ) 知道的一个区域被表示。HSV miRNAs 的发现帮助画病毒的感染和致病的一幅更大的图画。这评论总结到目前为止在 HSV-1 和 HSV-2 发现的 miRNAs。在到日期的 HSV 的 miRNAs 的功能的研究显示他们起与病毒的蛋白质协调维持病毒生命周期的一个阶段特定的作用。
Herpes simplex virus (HSV) is a group of common human pathogens with two serotypes HSV-1 and HSV-2. The prevalence of HSV is worldwide. It primarily infects humans through epithelial cells, when it introduces a latent infection into the nervous system. During viral latency, only a region known as the latency-associated transcript (LAT) is expressed. The discovery of HSV miRNAs helps to draw a larger picture of the infection and pathogenesis of the virus. This review summarizes miRNAs found in HSV-1 and HSV-2 so far. The functional studies of miRNAs in HSV to date indicate that they play a stage-specific role coordinated with viral proteins to maintain the virus life cycle.