中文摘要：

利用电喷雾离子阱质谱研究了三聚吡咯／丝组缀合物的质谱裂解规律，结果发现：主要裂解途径包括环系与羰基之间的碳碳键断裂、酰胺键断裂以及碳氮键的断裂；如果一个化合物的多级质谱具有特征的[M—100]^＋碎片离子，那么该化合物很有可能含有Boc官能团；如果一个化合物的多级质谱同时具有特征的[M—100]^＋碎片离子和[M-137]^＋碎片离子，那么该化合物很有可能是含有Boc保护的组氨酸的化合物。

英文摘要：

MS/MS fragmentation pathways of polyamide/peptide conjugates, which are synthetic analogues of natural products with DNA affinity are discussed. The main fragmentation pathways involve the cleavage of the C-CO between rings and carbonyl groups, CO-NH amide bonds and NH-C bond between the NH groups and the ring. The fragment ions at [M-100]^＋ in the MS/MS spectra of the [M＋ H]^＋ ions of compounds prove the compound containing his group. If the MS/MS spectra of a compound shows characteristic [M-100]^＋ ions and [M-137]^＋ ions, that means this compound has a histidine containing Boc group.