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中文摘要：
利用片断合成法合成了具有DNA切割能力的六聚吡咯／丝组缀合物，检测了该化合物的^1H、^13C NMR和ESI—MS／MS图谱，确证了该化合物的结构，通过^1H—^H COSY，HSQC，HMBC等2D NMR技术对其^1H和^13C NMR数据进行了归属和解析，并探讨了其ESI—MS／MS质谱裂解规律．
英文摘要：
A hexpolyamide/seryl-histidine dipeptide coniugate DNA cleavage agent was synthesized and its structure was elucidated by NMR and ESI-MS/MS methods. Com- plete assignment of ^1 H and ^13C NMR chemical shifts of the compound was obtained using 2D NMR techniques, including 1^H-^1H COSY, HSQC and HMBC. The MS/MS fragmentation pathways of the polyamide/peptide conjugate are also discussed.
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