目的:利用文本挖掘技术探索中成药、西药对慢性胃炎的治疗规律。方法:在中国生物医学文献数据库(CBM)中收集治疗慢性胃炎的相关文献,建立Access数据库,运用SQL对数据进行处理,结合人工降噪,分析中成药、西药对再障的治疗用药规律。结果:四逆散、理中丸等为中成药治疗慢性胃炎文献中出现的高频药物,阿莫西林、奥美拉唑、克拉霉素等为西药治疗慢性胃炎文献中出现的高频药物,在药物联合应用方面,中药四逆散、西药雪尼替丁和奥美拉唑出现频率较高。结论:利用文本挖掘技术可以从海量的中成药文献中发现治疗慢性胃炎的用药规律,协助规范中西医联合治疗方案。
Objectine: To analyze the regularity of Chinese patent medicine and west medicine application for chronic gastritis with text mining technique.Method: Collected large literature about treatment against chronic gastritis in CBM(Chinese Bio Medical Literature Database).Then,We transfer XML type data sets to the structured database of Microsoft SQL and visualize them into different graphs by Excel and Cytoscape software.Result: Sini San,Lizhong Wan were the commonly used Chinese patent medicine.The high frequencies of west medicine against chronic gastritis were amoxicillin,omeprazole and clarithromycin.Chinese patent medicine Sini San as well as west medicine omprazde and ranitidine of the combinated with othor drugs in treatment of the chronic gastrits.Conelusion: The text mining technology can find the medication regularity of Chinese patent medicine and west medicine application for chronic gastritis.