宫颈癌是女性常见的恶性肿瘤,严重影响妇女的生活质量。人乳头状瘤病毒感染是宫颈癌的主要致病因素,近几年的研究发现p53 codon 72多态性与宫颈癌的发生发展密切相关。现主要综述该位点多态性在宫颈癌发生机制中的研究进展。
Cervical cancer which has seriously affected women' s life quality is female's common malignant tumor. The human papillomavirus is main pathogenesis factor of cervical cancer. Recently researches find there are intimate relation between p53 codon 72 polymorphism and cervical cancer. Now we mainly summarize the research progress of the polymorphism in the mechanism of cervical cancer.