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中文摘要：
针对中药质量生物评价与控制中面临的重要技术问题——生物测定方法，以黄连质量生物评价与控制（抑菌活性）为代表性实例，从方法学内涵、选择原则、实验设计、数据分析等方面，对融合生物效价值和生物效应谱表征技术为一体的抑菌活性检测的新方法建立过程及应用进行阐释，以期为构建基于道地药材和生物测定的中药质量控制模式与方法提供技术参考。
英文摘要：
Establishment of bioassay methods is the technical issues to be faced with in the bioassay of Chinese materia medica. Taking the bioassay of Coptis chinensis Franch. as an example, the establishment process and application of the bioassay methods （including bio-potency and bio-activity fingerprint） were explained from the aspects of methodology, principle of selection, experimental design, method confirmation and data analysis. The common technologies were extracted and formed with the above aspects, so as to provide technical support for constructing pattern and method of the quality control for Chinese materia medica based on the Dao-di herbs and bioassay.
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