中文摘要：

瞄准：与急躁的肠症候群(IBS ) 在女人的生活(QoL ) 的症状和质量探索年龄相关的变化。方法：二 -- 有在在 2008 年 1 月和 2008 年 10 月之间的南京医药大学的首先隶属于的医院出席肠胃病学的部门的 IBS 的 154 个女成年门诊病人被接近。有最近服了治疗精神病的药的腹的外科，精神病或那些的历史的病人被排除。一位医生获得了人口统计、腹的症状数据。所有病人被要求完成自我评估的焦虑和消沉放大的 Zung (SDS/SAS ) 和 IBS 特定的 QoL 问询表。病人根据年龄被划分成六个组，在 10 年的增长：18-27 年， 28-37 年， 38-47 年， 48-57 年， 58-67 年和 68-75 年(最大值 75 年) 。腹的疼痛或不快的年龄相关的差别用等级和测试被分析。在在年龄组之间的 SDS/SAS 和 IBS-QoL 分数的差别用变化的单程的分析被分析。皮尔森关联在每个年龄组评估了在 IBS 症状，心理因素和 QoL 之间的潜在的协会。结果：在在年龄组之间的 IBS 子类型的分发没有差别(2 = 20.516， P = 0.153 ) 。在有年龄的腹的疼痛 / 不快的严厉的差别是统计上重要的(2 = 25.638， P < 0.001 ) ；48-57 年， 58-67 年或 68-75 年的病人在更年轻的年龄组比那些有更温和的腹的疼痛 / 不快。焦虑或压抑的症状的严厉没在年龄组之间不同(SDS， 2 = 390.845， P = 0.110；SAS， 2 = 360.071， P = 0.220 ) 。IBS-QoL 分数的差别在年龄组之间是统计上重要的(2 = 1098.458， P = 0.011 ) 。在 48-57-year 组的病人的分数是比在 18-27-year 和 28-37-year 组的那些低的(48-57-year 组对 18-27-year 组， 74.88 ?? 敦瑥吗？

英文摘要：

AIM：To explore age-related changes in symptoms and quality of life（QoL） of women with irritable bowel syndrome（IBS）.METHODS：Two-hundred and fifty-four female adult outpatients with IBS attending the Department of Gastroenterology at the First Affiliated Hospital of Nanjing Medical University between January,2008 and October,2008 were approached.Patients with a history of abdominal surgery,mental illness or those who had recently taken psychotropic drugs were excluded.A physician obtained demographic and abdominal symptom data.All patients were asked to complete the Zung Self-Rated Anxiety and Depression Scale（SDS/SAS） and the IBS-specific QoL questionnaire.The patients were divided into six groups according to age,in 10-year increments：18-27 years,28-37 years,38-47 years,48-57 years,58-67 years and 68-75 years（maximum 75 years）.Age-related differences of abdominal pain or discomfort were analyzed using ranksum tests.Differences in SDS/SAS and IBS-QoL scores between age groups were analyzed using one-way analysis of variance.Pearson＇s correlations evaluated potential associations between IBS symptoms,psychological factors and QoL in each age group.RESULTS：There were no differences in the distribution of IBS subtypes between age groups（χ2 = 20.516,P = 0.153）.Differences in the severity of abdominal pain/discomfort with age were statistically significant（χ2 = 25.638,P 〈 0.001）;patients aged 48-57 years,58-67 years or 68-75 years had milder abdominal pain/discomfort than those in the younger age groups.The severity of anxiety or depressive symptoms did not differ between age groups（SDS,χ2 = 390.845,P = 0.110;SAS,χ 2 = 360.071,P = 0.220）.Differences of IBSQoL scores were statistically significant between age groups（χ2 = 1098.458,P = 0.011）.The scores of patients in the 48-57-year group were lower than those in the 18-27-year and 28-37-year groups（48-57-year group vs 18-27-year group,74.88 ± 8.76 vs 79.76 ± 8.63,P = 0.021;48-57-year group vs 28-37-year group,74.88 ±