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Biosynthesis of Bioadaptive Materials： A Review on Developing Materials Available for Tissue Adaptation

ISSN号：1005-0302
期刊名称：《材料科学技术学报：英文版》
时间：0
分类：TB3[一般工业技术—材料科学与工程] Q813[生物学—生物工程]
作者机构：[1]Department of Orthopaedic, Peking University Shenzhen Hospital, Shenzhen 518036, China, [2]Department of Spinal Surgery/Orthopaedic Research Institute, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China, [3]Orthopaedic Research Lab/The Institute of Clinical Medicine, Aarhus University Hospital, 8000 Aarhus C, Denmark
相关基金：This study was supported by the National Basic Research Program of China （973 Program, No. 2012CB619105）, the China Postdoctoral Science Foundation （Nos. 2013M531876 and 2014T70826）, the National Natural Science Foundation of China （Nos. 31430030, 81272041, 81071512 and 31170902）, the Natural Science Foundation of Guangdong Province （Nos. 2014A030310466 and 2013B060300007）, the Foundation of Shenzhen Committee for Science and Technology Innovation （Nos. CXZZ20130516103023168 and 2015-336,2013-950）, the Jiangxi Province Science and Technology Support Plan Project （No. 2010BSA14800） and the Guangdong Provincial Key Laboratory of Orthopaedics and Tranmstology.

作者： Junxuan Ma[1,2], Zhiyu Zhou[2], Manman Gao[2], Binsheng Yu[1], Deming Xiao[1], Xuenong Zou[2], Cody Bunger[3]

关键词：材料合成, 组织, 综述, 免疫排斥反应, 生物材料, 合成材料, 微环境, 稳定性, Biomaterials Bioadaptation Tissue integration Biosynthesis

中文摘要：

Biomaterials are increasingly being evolved to actively adapt to the desired microenvironments so as to introduce tissue integration, reconstruct stability, promote regeneration, and avoid immune rejection.The complexity of its mechanisms poses great challenge to current biomimetic synthetic materials. Although still at initial stage, harnessing cells, tissues, or even entire body to synthesize bioadaptive materials is introducing a promising future.

英文摘要：

Biomaterials are increasingly being evolved to actively adapt to the desired microenvironments so as to introduce tissue integration, reconstruct stability, promote regeneration, and avoid immune rejection. The complexity of its mechanisms poses great challenge to current biomimetic synthetic materials. Although still at initial stage, harnessing cells, tissues, or even entire body to synthesize bioadaptive materials is introducing a promising future.

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