研究水溶性壳聚糖水溶液的相行为,通过改变体系温度和水溶性壳聚糖质量分数,形成两种有序聚集体。进一步测定两种有序聚集体在不同温度下的稳态和动态流变性质。在此基础上,以本体系中的聚集体为载体,测定两种不同聚集体对VC的缓释和稳定性作用。结果表明:从两种聚集体的稳态流变发现两种聚集体均具有较强的假塑性。聚集体I的动态流变曲线在低频下符合Maxwell模型,频率增大后则表现为弹性体;而聚集体II在测量频率范围内损耗模量(G″)小于贮能模量(G′),表现出黏弹性行为。另外缓释和稳定性实验结果表明,两种聚集体均对VC起到很好的缓释和稳定作用。
Two ordered assemblies of water-soluble chitosan were formed in aqueous solution at various chitosan concentrations and temperatures. Steady and dynamic rheological properties of both assemblies were investigated at different temperatures. Meanwhile, the effect of both assemblies as separate carriers for vitamin C on sustained release and stability of vitamin C was determined. The steady rheological curves indicated that both assemblies had strong pseudoplastic property. The dynamic rheological curves revealed that the assembly I could be fitted with Maxwell model under the condition of low frequency and performed as an elastomer under the condition of high frequency. In the tested frequency range, the loss modulus(G ″) of the assembly II was always lower than its storage modulus(G ′ ) . Therefore, both assemblies allows sustained release and stability maintenance of vitamin C.