炎症性肠病(innammatory bowel disease,IBD)是一组病因未明的以慢性胃肠道炎症为特征的疾病,包括克罗恩病(Crohn’s disease,CD)和溃疡性结肠炎(ulcerative colitis,uc)。细胞因子在IBD肠道炎症反应和黏膜免疫反应中起重要作用,目前已成为研究IBD发病机制的热点,本文就其在IBD中的作用作一综述。
Inflammatory bowel disease (IBD), which mainly includes ulcerative colitis (UC), represents a group of idiopathic diseases characterized by chronic inflammation of the gastrointestinal tract. Cytokines play an important role in intestine inflammation and mucosal immune response of IBD, and have become a hot research in the pathogenesis of IBD. The role of cytokines in IBD will be introduced in this review.