中文摘要：

为了更有针对性地研究鸣禽高级发声中枢（HVC）性双态性的形成过程,本文以白腰文鸟（Lonchura striata）为实验对象,首先通过vimentin免疫组织化学分析端脑HVC区域放射胶质细胞纤维的起源与走向,推断出幼鸟孵化后的HVC正背侧VZ区为HVC细胞的主要发源位点;在此基础上,对15d幼鸟经由胸大肌注射^3H-胸腺嘧啶以标记端脑新生细胞,通过^3 H放射性自显影技术比较雌、雄HVC干细胞的增殖能力,充分证明了HVC细胞发源点的神经干细胞细胞增殖能力具有显著的性别差异.

英文摘要：

To analyze mechanism of sexually dimorphic development of high vocal center （HVC） in songbird, it was confirmed that ventricular zone （VZ） dorsal to HVC was an important source of HVC cells, and their migratory route was identified by the distribution of radial glial cells in telencephalon in Lonchura striatu with vimentin antibody immunohistology; Male and female Lonchura striatu 15 d post-hatching received intramuscular injection of ^3 H-thymidine, the number of newborn cells in VZ dorsal to HVC was counted by ^3 H- thymidine autoradiography. Such data proved remarkable sex difference in cell proliferation in the origin of HVC cells.