中文摘要：

目的充分发挥广州市计生服务网络优势，探索建立以人口计生公共服务网络为主体、以医疗保健技术资源为支撑的家庭生殖健康促进模式的可行性。方法①在现有人口管理及服务网络基础上，采取知情同意原则，自2013年11月-2014年12月31日对广州市南沙区万安村、雁沙村育龄期（女方结婚至年龄〈50岁）夫妇以及其胎、婴幼儿期（6岁前）儿童建立家庭纸质和电子档案及进行健康教育；②根据人群生殖健康处于不同阶段分别为其提供出生缺陷三级整体化干预服务、避孕节育技术服务、生殖保健全程管理与服务（包括女性LCT、HPV筛查、妇科检查及白带常规、妇科及乳腺B超；前列腺B超、性激素及PSA检测），筛查阳性家庭联合医疗服务机构提供咨询、转诊服务；③为具有生育功能障碍提供诊断和转诊服务。结果①出生缺陷三级整体化干预：参加孕前优生检查98个家庭中，有50个家庭筛查结果异常，优生咨询率为100．00％，已孕84个家庭中，早孕随访率为100．00％，唐氏筛查率为61．90％，高风险家庭2个，产前诊断为正常，B超重大畸形筛查率为66．67％，无高风险家庭，妊娠结局随访率为100．00％，2例自然流产，1例宫外孕，孕前及产前地贫筛查阳性率为10．08％，无地贫高风险家庭。②避孕节育落实措施率为100．00％，避孕节育定期随访率为100．00％，避孕节育并发症发生率为0．05％，并发症处理率100．00％，目标家庭年度人流与出生比为0．16％；生殖保健参与率为67．89％，接受生殖保健的645例女性中，生殖道感染114例，乳腺疾病225例，宫颈疾病20例，宫颈HPV阳性11例，其他疾病包括（子宫肌瘤或卵巢囊肿等）121例，接受生殖保健的60例男性中，包皮过长25例，精索静脉曲张4例，前列腺钙化12例，前列腺肥大6例，右侧阴囊肿物1例，生殖保健结果

英文摘要：

Objective To take advantage of family planning service network in Guangzhou city, explore the feasibility of establishing family reproductive health promotion pattern with population and family planning public service network as the main body and health care technology resources as its sustentation. Methods Based on the existing family planning service network, the couples of childbearing age （from maternal marriage time to less than 50 years old） whose children （before 6 years old） established health records of paper and electron- ic files and received health education in Nansha village and Wan＇an village of Nansha District in Guangzhou city from November 2013 to De- cember 31st in 2014 were selected according to the principle of informed consent. Birth defects intervention service, contraception technology service, full range management and service of reproductive health care （including LCT, HPV screening, gynecological examination, leu- corrhea, gynecological and breast ultrasonography; prostate uhrasonography, sex hormones examination and PSA test） were provided during different periods. Counseling and referral services were provided for the families having positive result by medical service institutions. Diag- nosis and transfer service were provided for the cases with reproductive dysfunction. Results Integrated three-level intervention of birth de- fects： among 98 families received pre-pregnancy examination, 50 families had abnormal screening results, the rate of eugenic consultation was 100.00%. Among 84 families of pregnancy, the follow-up rate of early pregnancy was 100.00%, the screening rate of Down＇s syn- drome was 61.90%, two high-risk families were found, the result of prenatal diagnosis was normal, the screening rate of major malforma- tions by ultrasonography was 66. 67%, no high-risk family was found, the follow-up rate of pregnancy outcome was 100. 00%, adverse pregnancy 0uteomes included 2 cases of spontaneous abortion and 1 case of ectopic pregnancy. The positive rate of tha