欢迎您！东篱公司
退出
-
申报数据库
-
立项数据库
-
成果数据库
-
项目获奖数据库
中文摘要：
建立了血液样品中多溴联苯醚的分析方法。血液样品采用离心和分离，提取血清。血清经过正己烷和甲基叔丁基醚的混合溶液（体积比1：1）萃取，萃取前加入回收率指示物，然后经干燥得到脂肪重量；脂肪再经正己烷溶解、酸洗和酸性硅胶柱（硅胶与浓硫酸的重量比为2：1）净化后，加内标，进气相色谱-负化学离子源．质谱（GC-NCI-MS）联用仪，采用选择离子检测（SIM）法和内标法定性和定量。结果表明加标回收率为76．0％～106．0％；方法检出限0．01—0．1ng；仪器检出限为0．5～2．0Pg。该方法检测血液中8种多溴联苯醚的同系物，灵敏度高、重现性好和回收率良好，可用于人体血液样品的检测。
英文摘要：
A method was developed for the determination of seven congeners of polybrominated diphenyl ethers （PBDEs） in human blood by gas chromatography-negative chemical ionization-mass spectrometry （GC-NCI-MS） in the selected ion monitoring mode. Human serum samples were extracted with hexane-methyl tert-butyl ether （MTBE） （ volume ratio is 1 ： 1 ）. The organic phases were washed with potassium chloride solution, followed by evaporation to dryness for gravimetric determination of extracted lipid content. Lipid was dissolved with n-hexane and washed with H2SO4, and then samples were cleaned up with a silica/sulfuric acid column （2：1 by weight）. Internal standard was added prior to GC-MS analysis. The results indicate that the average recovery of the internal standard was from 76.0% to 106.0%. The detection limit of the method was in the range of 0.01 -0.1 ng; The detection limit of instrument was 0.5 -2.0 pg. The method for detection of eight PBDE congeners in human blood was sensitive, high reproducible with satisfied recoveries.
同期刊论文项目
同项目期刊论文
Characterization and the photocatalytic activity of TiO2 immobilized hydrophobic montmorillonite pho
Pollution characterization and diurnal variation of PBDEs in the atmosphere of an E-waste dismantlin
Effects of tetrabrominated diphenyl ether and hexabromocyclododecanes in single and complex exposure
Selection of benthic macroinvertebrate-based multimetrics and preliminary establishment of biocriter
Elevated levels of urinary 8-Hydroxy-2#-deoxyguanosine in male electrical and electronic equipment d
Sources and characteristics of carbonaceous aerosol in two largest cities in Pearl River Delta Regio
Atmospheric deposition of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in Guangzhou
Preliminary study on the occurrence and distribution of polycyclic musks in a wastewater treatment p
Polybrominated diphenyl ethers and organochlorine pesticides in sewage sludge of wastewater treatmen
Determination of hexabromocyclododecane diastereoisomers in air and soil by liquid chromatography-el
Establishment and Application of the Co-analysis Method of PBDD/Fs and PCDD/Fs with Isotope Dilution
Development of a Compound-Specific Isotope Analysis Method for Atmospheric Formaldehyde and Acetalde
Development of a compound-specific carbon isotope analysis method for atmospheric formaldehyde via N
Site determination of phenyl glycidyl ether-DNA adducts using high-performance liquid chromatography
Concentration levels, compositional profiles, and gas-particle partitioning of polybrominated diphen
Improvement of 2,4-dinitrophenylhydrazine derivatization method for carbon isotope analysis of atmos
Exposure to polybrominated diphenyl ethers among workers at an electronic waste dismantling region i
In- and outdoor sources of polybrominated diphenyl ethers and their human inhalation exposure in Gua
Infrared Spectral Analysis of MCF-7 Cells Treated with Serum-Lipid Extracts Segregates Predominantly
Concentrations, profiles and gas-particle partitioning of polychlorinated dibenzo-p-dioxins and dibe
Phenols and hydroxyl-PAHs (Arylphenols) as Tracers for Coal Smoke Particulate Matter: Source tests a
Enhancement of phenanthrene and pyrene degradation in rhizosphere of tall fescue (Festuca arundinace
PBBs, PBDEs, and PCBs levels in hair of residents around e-waste disassembly sites in Zhejiang Provi
Predicting bioavailability and accumulation of organochlorine pesticides by Japanese medaka in the p
Comparison of the Uptake of Polycyclic Aromatic Hydrocarbons and Organochlorine Pesticides by Semipe
Identification of Ah Receptor Agonists in Soil of E-waste Recycling Sites from Taizhou Area in China
High levels of heavy metals in rice (Oryza sativa L.) from a typical E-waste recycling area in south
Exposure of Electronics Dismantling Workers to Polybrominated diphenyl Ehters, Polychlorinated Biphe
位置：