中文摘要：

目的总结大疱性皮肤病的临床特点和治疗经验。方法对48例大疱性皮肤病住院患者的临床表现、实验室检查结果和临床疗效进行回顾性分析。结果本研究中48例大疱性皮肤病患者中有28例患者为大疱性类天疱疮,占总数的58.3%。大疱性类天疱疮患者中20例单独使用糖皮质激素治疗的患者皮损痊愈8例,好转11例,治愈率40%;糖皮质激素联合丙种球蛋白（IVIG）治疗的4例患者中,3例达到皮损痊愈,治愈率75%。大疱表皮松解型药疹患者中4例单独使用糖皮质激素治疗的患者皮损痊愈2例,好转2例,治愈率50%;糖皮质激素联合丙种球蛋白（IVIG）治疗的6例患者中,4例达到皮损痊愈,1例好转,治愈率66.7%。结论本研究提示大疱性类天疱疮是大疱性皮肤病中最常见的一类疾病;糖皮质激素在大疱性皮肤病治疗中的疗效肯定,且注射丙种球蛋白是一种重要的支持治疗方法。

英文摘要：

Objective To summarize the clinical features and effective treatment for bullous dermatosis.Methods The clinical data of 48 cases with bullous dermatosis was analyzed retrospectively.Results There were 28 case of bullous pemphigoid in the 48 case of bullous dermatosis of the study,accounting for 58.3% of the total.Among 20 cases of bullous pemphigoid using corticosteroids alone,8 cases were cured and 11 cases were improved,the cure rate was 40%;among 4 cases of bullous pemphigoid treated with intravenous immunoglobulin（IVIG） together with corticosteroids,3 cases were cured,the cure rate was 75%.Among 4 cases of bullous epidermolysis drug eruption with the treatment of corticosteroids alone,2 cases were cured and 2 cases were improved,the cure rate was 50%;among 6 cases of bullous epidermolysis drug eruption using intravenous immunoglobulin（IVIG） together with corticosteroids,4 cases were cured and 1 cases were improved,with cure rate 66.7%.Conclusion The study suggested that bullous pemphigoid was the most common type of disease in bullous dermatosis.The curative effect of application of corticosteroids was positive in the treatment of bullous dermatosis,and the treatment with intravenous immunoglobulin（IVIG） was an important supportive treatment.