中文摘要：

大动物及人降低体温有利于对中枢神经系统缺血和其他外伤性损伤的恢复。低温治疗的效果受体温降低类型的影响（调节性和非调节性）。许多不同病理生理性伤害可引起啮齿类动物调节性低温反应。目前认为，调节性低体温可能是取得低温治疗最好的手段。本文就调节性低温的病理生理意义和精氨酸加压素在调节低温中的作用及其可能机制作一综述。

英文摘要：

Larger species, including humans, may benefit from a lower body temperature when recovering from CNS ischaemia and other traumatic insults. The therapeutic efficacy of the hypothermic treatment is likely to be influenced by the nature of the reduction in body temperature （that is, forced versus regulated）. Rodents subjected to many types of pathophysiological insults undergo a regulated hypothermic response. Regulated hypothermia would seem to be the best means of achieving a therapeutic benefit. This review focuses on pathophysiological significance of regulated hypothermia, and role of arginine vasopressin in regulated hypothermia and its mechanisms.