目的:运用聚类分析研究广泛性焦虑症的中医证候学规律。方法:2009年8月1日至2010年7月31日,在北京地区10家分中心进行了为期1年、705例广泛性焦虑症患者的中医证候学观察,通过专家组指导,运用聚类分析方法分析广泛性焦虑症的中医证候学规律。结果:运用聚类分析提取了8个证候类型,分别为肝郁化火、肾精亏虚、心胆气虚、心血亏虚、气血两虚、痰湿困脾、阴阳两虚、气郁血瘀。结论:聚类分析在挖掘中医证候规律等方面具有一定的应用前景,适合应用于中医证候规律的研究。
Objective: To analyze the rule of traditional Chinese medicine syndrome of generalized anxiety disorder(GAD) by cluster analysis. Methods: The syndrome of 705 GAD patients were investigated in 10 hospitals in Beijing within 1 year from August 1st, 2009 to July 31th, 2010, and cluster analysis was used to analyze the syndrome discipline of generalized anxiety disorder. Results: 8 syndromes of GAD was extracted by cluster analysis, such as depression of the liver generates pathogenicfire, deficiency of kidney-essence, type of deficiency of heart and gallbladder, insui ciency of the blood of the heart, deficiency of both qi and blood, accumulation of phlegm-wetness in the body, deficiency of both yin and yang, depressed qi lead to blood stasis. Conclusion: Cluster analysis has certain application prospect in excavating the rule of TCM syndrome, and it is suitable for the research of syndrome discipline.