中文摘要：

以脱镁叶绿酸-a甲酯为起始原料,利用周环上的碳碳、碳氧和烯醇式复健,通过加成、取代、缩合和空气氧化等化学反应在色基上构建手性中心、顺反结构和阻旋位点.经过旨在扩大立体差异的化学修饰,对部分差向异构体进行了有效分离,完成一系列具有立体异构特征的叶绿素衍生物的合成,并通过UV,IR,1H NMR及元素分析证实了11个未见报道的二氢卟吩衍生物的化学结构,同时对不同立体异构的形成及其表征进行了讨论.

英文摘要：

Pheophorbide-a methyl ester was used as a starting material, and chiral center, cis-trans structure and atropisomic position were established on the chromophore making use of carbon-carbon, carbon-oxygen and enol form double bond. A series of synthesis of chlorophyllous derivatives possessing stereo-isomeric character were completed by addition, substitution, condensation and allomerization. The part of epimers were separated from each other effectively after chemical modification for expanding stereo-differences. The chemical structures of 11 unreported chlorins related to chlorophyll were characterized by elemental analysis, UV, IR and 1H NMR spectra. The formations of different steric isomerism and their identifications were also discussed.