介绍了震荡热管应用于玻璃化保存的新方案,建立了生物组织在玻璃化保存过程中的数学模型,通过ANSYS分析软件,对样品在降温过程中的温度场进行了计算分析和数值模拟。得出了生物组织的瞬时温度分布,并通过模拟结果,计算出了生物组织在降温过程中的降温速率可达2×10^4℃/s。研究结果表明:极快速的降温速率可使细胞或组织快速通过0℃--60℃的危险温度区域,从而抑制冰晶的生成和长大,减轻胞内冰造成的细胞损伤。
The new program of oscillating heat pipe (OHP)applied in vitrification preservation was introduced, and a mathematical model for biological tissue in vitrification was developed. Through the analysis software ANSYS, the calculated analysis and numerical simulation on the distribution of temperature field in cells cooling process were made. The transient temperature distribution in biological tissues was obtained, and through the simulation results, the cooling rate of biological tissues in cooling process was up to 2 × 10^4℃/s. The results show that very fast cooling can make cells or tissues move swiftly through the dangerous temperature region of 0 % - -60 ℃ , which restrained the formation or growth of ice crystals and reduced cells damage caused by intracellular ice.