寡霉素抗生素组合物是一类二十六元环大环内酯类抗生素,具有强烈的抗肿瘤、抗真菌、呼吸抑制作用及杀虫等生物学活性,被广泛应用于科学研究当中。本文对寡霉素的生物学活性、产生菌及生物合成的研究进展进行了综述。
Oligomycins are a series of 26-membered macrocyclic lactones. They display strong antifungal, antitumor, respiratory inhibitory and insecticidal activities, and are widely used in scientific research. In this paper, we review the research advances in the biological activities, producing strains and biosynthesis of oligomyicns.