HIV蛋白酶是病毒复制的必需酶,是寻找治疗获得性免疫缺陷病药物的重要靶点之一。本文对HIV蛋白酶抑制剂的特点、临床药效及不良反应的研究近况进行归纳总结并作此综述。
HIV protease is the essential enzyme for viral replication, and one of important targets in looking for anti-AIDS drugs design and research. We summarized and reviewed the present status of characteristics, clinical efficacy and adverse reactions of HIV protease inhibitors.