以香草醛为起始原料,在乙醇溶液中和1,2-二溴乙烷反应生成1,2-二(4-甲酰-2-甲氧基苯氧基)乙烷,再依次对其进行硼氢化和质子化,三步合成笼状超分子主体化合物穴番-A,产物通过硅胶柱分离纯化后用核磁光谱对其进行了分析鉴定,并且用荧光和紫外光谱对它的发光性能进行了研究。
Cryptophane-A was synthesized from vanillin using a three-step method and purified by elution through a silica gel column. The structure was characterized by nuclear magnetic resonance (NMR) spectroscopy. Cryptophanes consist of two rigid cone-shaped units (cyclotriveratrylene) linked together by three bridges. The fluorescence and UV spectra were studied. It can complex with neutral molecules and plays an important part in molecular probe and gas sensor field.