中文摘要：

将纳米羟基磷灰石／聚酰胺66（n-HA／PA66）复合材料与抗生素类药物头孢哌酮钠（cefoperazone Sodium）复合，用特定溶剂将其调成糊状并自固化后，对该复合材料负载抗生素后的理化特性进行了研究。通过红外光谱及X射线衍射分析显示，载药材料保持了良好的化学稳定性。扫描电镜图象显示，材料表面及内部结构多孔。自固化n-HA／PA66复合材料在骨修复药物载体方面有很好的开发和应用前景。

英文摘要：

A novel drug-controlling release system has been set up using cefoperazone sodium （CES） as a model drug and nano-hydroxyapatite/polyamide66 composite （n-HA/PA66） with self-setting property as the carrier, and the physico-chemical properties were characterized by means of IR, XRD and SEM. The results indicated that there was no obvious influence on the physio-chemical properties of the self-setting n-HA/PA66 composite after being loaded drug. The set composite showed porous structure, which was desirable for drug release from it. Furthermore, both the interior and exterior structures of the drug-containing material have not changed evidently. It can be concluded that the drug-containing composite has a potential to be utilized as local drug-controlled release carrier.