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BLM蛋白解旋活性中心的DNA解旋动力学机理研究
  • 期刊名称：生物物理学报
  • 时间：0
  • 页码：321-
  • 分类：R596[医药卫生—临床医学;医药卫生—内科学]
  • 作者机构：[1]中国科学院物理研究所, [2]法国居里研究所(INSTITUT CURIE)
  • 相关基金：国家自然科学基金委项目资助(30770517,10674173)
  • 相关项目：利用单分子和荧光方法研究生物大分子的动力学
作者： 杨晔|窦硕星|王鹏业|徐雅楠|奚绪光|
关键词： 解旋酶, BLM蛋白, DNA解旋, 动力学机理
中文摘要：

Bloom综合症(Bloom’s syndrome)是一种罕见的常染色体隐性遗传基因不稳定性综合征,能够增加患者对各种癌症的易感性[1]。因突变而导致Bloom综合症的BLM基

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