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中文摘要：
分子的梳是为排列 DNA 分子到表面上的一个强大、简单的方法。用与荧光显微镜学相结合的这种技术， DNA-histone 建筑群在恐水病的 polymethyl methacrylate (PMMA ) 上被拉长表面并且直接观察了。我们开发了一个新方法拉长单个 DNA-histone 建筑群，称为拉长纺纱。结果证明 histones 显著地提高对 PMMA 表面有约束力的 DNA。DNA 在 histones 附近弯屈因此在长度减少。histones 的数字绑在每个 DNA 分子被发现与 histone 集中相关。combed DNA-histone 建筑群被发现取决于二个因素：表面上的有约束力的力量和在它的本地位置的离心的力量。Na+ 离子应该为绑定与 histones 竞争到 DNA；然而，在低集中的 Na+ 离子的观察竞争有约束力的效果是可以忽略的。
英文摘要：
Molecular combing is a powerful and simple method for aligning DNA molecules onto a surface. Using this technique combined with fluorescence microscopy, DNA-histone complexes are stretched on a hydrophobic polymethyl methacrylate （PMMA） sur- face and observed directly. We have developed a new method to stretch single DNA-histone complexes, termed spin-stretching. The results show that the histones markedly enhance DNA binding to the PMMA surface. DNA winds around the histones and therefore decreases in length. The number of histones that bind to each DNA molecule is found to correlate with the histone con- centration. The combed DNA-histone complexes are found to depend on two factors： the binding force on the surface and the centrifugal force at its local position. Na＋ ions should compete with histones for binding to DNA; however, the observed competi- tive binding effect of Na＋ ions at low concentrations was negligible.
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