位置：成果数据库 > 期刊 > 期刊详情页
Studies on Molecular Interactions between Puerarin and PC Liposomes
  • 时间：0
  • 分类：TQ460.69[化学工程—制药化工]
  • 作者机构：[1]School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China
  • 相关基金：Supported by the National Natural Science Foundation of China （Grant No. 20633010）
  • 相关项目：溶液中两亲分子有序组合体的构筑规律及其在生命科学相关领域中的应用
关键词： 葛根黄素, 卵磷脂, 脂质体, 药物包装, puerarin, phosphatidylcholine, liposome, drug encapsulation
中文摘要：

荧光排放系列， FTIR 系列，希腊语的第六个字母潜力大小，和 ab initio 量计算被用来学习在 puerarin 之间的相互作用，膜鸡蛋 phosphatidylcholine (PC ) 创作了脂肪一些。疏水性互动原因与它的 B-ring 划分成类脂化合物双性人层，并且向词根赞成 puerarin 的酸碱平衡的排水量的 puerarin 分子。由于在 puerarin 氢氧根组和水 / 膜接口上的 PC 分子的极的组之间的氢键形成， puerarin 能容易设置进 phospholipids 的组织结构并且调制膜函数。我们的结果表明脂肪的一些膜正直与的相比是显著地更高的空脂肪一些。

英文摘要：

Fluorescence emission spectra, FTIR spectra, zeta potential measurements, and ab initio quantum calculation are used to study the interaction between puerarin and membranes composed of egg phosphatidylcholine （PC） liposome, The hydrophobic interactions cause the puerarin molecule to par- tition into lipid bilayers with its B-ring, and favor the displacement of acid-base equilibrium of puerarin towards the base form, Due to the hydrogen bond formation between the puerarin hydroxyl groups and polar groups of PC molecules on the water/membrane interface, puerarin can easily intercalate into the organized structure of phospholipids and modulate the membrane function, Our results reveal that the liposome membrane integrity is significantly higher compared with that of empty liposome,

同期刊论文项目
溶液中两亲分子有序组合体的构筑规律及其在生命科学相关领域中的应用
期刊论文 185 会议论文 127
同项目期刊论文
Recent Advances in the Mixed Systems of Bolaamphiphiles and Oppositely Charged Conventional Surfacta
Fluorescence Enhancement by Microphase Separation-Induced Chain Extension of Eu3+ Coordination Polym
Aqueous Self-Assembly of SDS@2β-CD Complexes: Lamellae and Vesicles
Rationally Designed Hierarchical Double Helix via Multiple Non-Covalent Interactions: Fabrication an
The Photodimerization of a Cinnamoyl Moiety Derivative in Dilute Solution Based on the Intramolecula
乙醇/水混合溶剂中Gemini表面活性剂的表面性质
Transfer and Distribution of L-tryptophan between W/O and O/W, and between W/O and Bicontinuous Micr
Interactions between Flavonoids and Hemoglobin in Lecithin Liposomes
Microstructure of Triton X-100/poly (ethylene glycol) Complex Investigated by Fluorescence Resonance
Aggregation Behaviors of a Series of Anionic Sulfonate Gemini Surfactants and Their Corresponding Mo
Modulation of Fibrillogenesis of Amyloid (1-40) Peptide with Cationic Gemini Surfactant
Adsorption of Hydrophobically Modified Poly(acrylamide)-co-(acrylic acid) on Amino-functionalized Su
“Annular Ring” microtubes formed by SDS@2 beta-CD complexes in aqueous solution
Unique Temperature-Dependent Supramolecular Self-Assembly: From Hierarchical 1D Nanostructures to Su
General Rules for the Scaling Behavior of Linear Wormlike Micelles formed in Catanionic Surfactant S
荧光探针技术在水溶液两亲分子有序组合体研究中的应用
Metal-Driven Viscoelastic Wormlike Micelle in Anionic/Zwitterionic Surfactant System and Template-Di
Selectivity and Stoichiometry Boosting of β-Cyclodextrin in Cationic/Anionic Surfactant Systems: Whe
Preparation and Visible-light Photocatalytic Activity of Mesoporous H3PW12O40/TiO2 Composite
Synthesis of Polyaniline/NiO Nanobelts by a Self-assembly Process
Synthesis of Poly(o-phenylenediamine) Hollow Spheres and Nanofibers Using Different Oxidizing Agents
Preparation of Zinc Gluconate Nanostructures with Different Shapes by Lamellar Liquid Crystal Templa
Microstructure and Lubrication Properties of Lamellar Liquid Crystal in Brij30/[Bmim]PF6/H2O System
Acid–base Equilibrium of Puerarin in CTAB Micelles
Fabrication of PbS Microstructures with Different Shapes in Aqueous Solutions of Amphiphilic Tribloc
Interaction between Casein and Sodium Dodecyl Sulfate
Microenvironment Effect on the Location Distribution of Phenothiazine in Cetyltrimethylammonium Brom
The Iinteraction between Hemoglobin and Two Surfactants with Different Charges
The Self-organization Properties of n-dodecylammoniumα-glutamate/n-C5H11OH/water System
Fabrication of Polymer Hollow Nanospheres by a Swelling–Evaporation Strategy
Decompaction of Cationic Gemini Surfactant-Induced DNA Condensates by β-Cyclodextrin or Anionic Surf
Micellization-Induced Conformational Change of a Chiral Proline Surfactant
Effect of Surfactant Structure on the Stability of Carbon Nanotubes in Aqueous Solution
pH-dependent Structures and Properties of Casein Micelles
Interaction between Casein and the Oppositely Charged Surfactant
Synthesis of Polymer Hollow Spheres with Holes in Their Surfaces
Polyaniline Hierarchical Structures Synthesized in Aqueous Solution: Micromats of Nanofibers
Combined Antioxidant Effects of Rutin and Vitamin C in Triton X-100 micelles
The Effect of Sodium Dodecyl Sulfate on the Conformation of Bovine Serum Albumin
Morphological and structural modulation of PbWO4 crystals directed by dextrans
Aggregation Behavior of a Tetrameric Cationic surfactant in Aqueous Solution
Molecular Conformation-Controlled Vesicle/Micelle Transition of Cationic Trimeric Surfactants in Aqu
Effects of Inorganic and Organic Salts on Aggregation Behavior of Cationic Gemini Surfactants
Highly Fluorescent Aggregates Modulated by Surfactant Structure and Concentration
Self-assembly of Peptide-Amphiphile C12-Aβ(11-17) into Nanofibrils
Aggregation properties of zwitterionic surfactants with different ionic headgroups, hydrophobic chai
Dilute Anionic Surfactant Solution Route to Polyaniline Rectangular Sub-microtubes as a Novel Nanost
Polymer-assisted crystallization and optical properties of uniform microrods of the organic dye Suda
Polyaniline Fan-like Architectures of Rectangular Sub-Microtubes Synthesized in Dilute Inorganic Aci
Controlled Synthesis of Pyramid-Aggregated Sphere-like Cadmium Sulfide in the Presence of a Polymer
Effect of Surfactant Structure on Catalysis of Microemulsion for Photoisomerization of Trans-stilben
Transfer and Distribution of L-tryptophan between W/O and O/W,and between W/O and Bicontinuous Micro
Structure of adsorbed layers of nitrophenoxy-tailed quaternary ammonium surfactants at the air/water
Aggregation Behavior of Nitrophenoxy-Tailed Quaternary Ammonium Surfactants
Fabrication of Polyaniline with Hierarchical Structures in Alkaline Solution
Comparative Studies on Adsorption Behavior of Thionine on Gold Nanoparticles with Different Sizes
Nanostructure-Based Leaf-like Polyaniline in the Presence of an Amphiphilic Triblock Copolymer
Polymer-controlled synthesis of silver nanobelts and hierarchical nanocolumns
Abnormal Interfacial Tension Behavior of Alkanediyl-αω-bis(dodecyldimethylammonium bromide) Gemini S
Synthesis of hollow PbS Nanospheres in Pluronic F127/cyclohexane/H2O Microemulsions
Aggregation properties of cationic gemini surfactants with dihydroxyethylamino headgroups in aqueous
Fabrication of Polymer Hollow Nanospheres by a Swelling–Evaporation Strategy
Modification of MnO2 Nanoparticles with Rutin Synthesized by Triton X-100 Aggregations’ Template
Fabrication of Novel CdIn2S4 Hollow Spheres via a Facile Hydrothermal Process
Growth of Dendritic Silver Crystals in CTAB/SDBS Mixed-Surfactant Solutions
Shape evolution of Cu2S nanostructures in Triton X-100/cyclohexane/water reverse micelles
Studies on the Antioxidant Effect of Rutin in the Microenvironment of Cationic Micelles
Micellization of Surfactin and Its Effect on the Aggregate Conformation of Amyloid β(1-40)
Highly-Ordered Selective Self-Assembly of a Trimeric Cationic Surfactant on a Mica Surface
PEG-Induced Lamellar-to-Isotropic Phase Transition in the System of TX-100/n-C8H17OH/H2O
A Simple One-Step Chemical Route to Gold/Polymer Core/Shell Composites and Polymer Hollow Spheres
Ionic Liquid Induced Transition from Wormlike to Rod or Spherical Micelles in Mixed Nonionic Surfact
Br?-Induced Facile Fabrication of Spongelike Gold/Amino Acid Nanocomposites and Their Applications i
Enhancement of Wormlike Micellar Structure Induced by O-Carboxymethylchitosan with or without Hydrop
Facile Fabrication of Pomponlike Microarchitectures of Lanthanum Molybdate via an Ultrasound Route
Constant Vapour Pressure Evaporation from a Fragrance Emulsion—Effect of Surfactant Content in the L
Stability versus Phase Ratios of Geranyl Acetate three-phase Emulsions
Initial Inter-phase Transport of Compounds in a Model Emulsion System
Nanoporous anatase TiO2 mesocrystals: additive-free synthesis, remarkable crystalline-phase stabilit
Facile fabrication of two-dimensionally ordered macroporous silver thin films and their application
Porous gold nanobelts templated by metal-surfactant complex nanobelts
Facile fabrication of honeycomb-patterned thin films of amorphous calcium carbonate and mosaic calci
Colloidal-crystal-assisted patterning of crystalline materials
Interaction of Methemoglobin with GDA/n-C5H11OH/water Assemblies
The Photostabilization of Hemoglobin in Triton X-100 Aqueous Solution and Triton X-100/n-C5H11OH/H2O
Transfer and Distribution of Methylene Blue through w/o-o/w and w/o-bicontinuous Interface
Novel Reactive Template Method to Synthesize Gold Nanoparticles with Controllable Size and Morpholog
Effect of Hydrotropic Salt on the Assembly Transitions and Rheological Responses of Cationic Gemini
Colloidal chemical approaches to inorganic micro- and nanostructures with controlled morphologies an
Solution-phase synthesis of one-dimensional semiconductor nanostructures
Synthesis and Properties of Novel Gemini Surfactant with Short Spacer
离子液体[BMim]BF4对SDS水溶液表面活性和聚集能力的促进
基于胱氨酸的Gemini型表面活性剂的合成及其性质
具有短连接基团的新型Gemini表面活性剂的合成与性质
葛根素与卵磷脂囊泡的相互作用