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溶液中两亲分子有序组合体的构筑规律及其在生命科学相关领域中的应用
  • 项目名称：溶液中两亲分子有序组合体的构筑规律及其在生命科学相关领域中的应用
  • 项目类别：重点项目
  • 批准号：20633010
  • 申请代码：B0305
  • 项目来源：国家自然科学基金
  • 研究期限：2007-01-01-2010-12-31
  • 项目负责人：黄建滨
  • 负责人职称：教授
  • 依托单位：北京大学
  • 批准年度：2006
中文摘要：

本课题将以溶液中两亲分子有序组合体的构筑规律及其在生命科学领域的应用为核心，着重开展生物相容两亲分子和与生命科学重要现象密切相关的两亲分子有序组合体的形成规律的研究，研究单一和多组分体系（包括两亲分子混合体系，两亲分子与聚合物及生物大分子，两亲分子与无机物种等）溶液中各类有序组合体的结构、性质与功能，认识有序组合体的构筑规律，发展相关的聚集体理论，拓展简单物化条件对有序组合体种类、形态的调控，了解

中文主题词： 两亲分子;有序组合体;溶液;构筑规律;生物相容
成果综合统计
成果类型
数量
  • 期刊论文
  • 会议论文
  • 专利
  • 获奖
  • 著作
  • 185
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期刊论文
Recent Advances in the Mixed Systems of Bolaamphiphiles and Oppositely Charged Conventional Surfacta
Fluorescence Enhancement by Microphase Separation-Induced Chain Extension of Eu3+ Coordination Polym
Aqueous Self-Assembly of SDS@2β-CD Complexes: Lamellae and Vesicles
Rationally Designed Hierarchical Double Helix via Multiple Non-Covalent Interactions: Fabrication an
The Photodimerization of a Cinnamoyl Moiety Derivative in Dilute Solution Based on the Intramolecula
乙醇/水混合溶剂中Gemini表面活性剂的表面性质
Transfer and Distribution of L-tryptophan between W/O and O/W, and between W/O and Bicontinuous Micr
Interactions between Flavonoids and Hemoglobin in Lecithin Liposomes
Microstructure of Triton X-100/poly (ethylene glycol) Complex Investigated by Fluorescence Resonance
Aggregation Behaviors of a Series of Anionic Sulfonate Gemini Surfactants and Their Corresponding Mo
Modulation of Fibrillogenesis of Amyloid (1-40) Peptide with Cationic Gemini Surfactant
Adsorption of Hydrophobically Modified Poly(acrylamide)-co-(acrylic acid) on Amino-functionalized Su
“Annular Ring” microtubes formed by SDS@2 beta-CD complexes in aqueous solution
Unique Temperature-Dependent Supramolecular Self-Assembly: From Hierarchical 1D Nanostructures to Su
General Rules for the Scaling Behavior of Linear Wormlike Micelles formed in Catanionic Surfactant S
荧光探针技术在水溶液两亲分子有序组合体研究中的应用
Metal-Driven Viscoelastic Wormlike Micelle in Anionic/Zwitterionic Surfactant System and Template-Di
Selectivity and Stoichiometry Boosting of β-Cyclodextrin in Cationic/Anionic Surfactant Systems: Whe
Preparation and Visible-light Photocatalytic Activity of Mesoporous H3PW12O40/TiO2 Composite
Synthesis of Polyaniline/NiO Nanobelts by a Self-assembly Process
Synthesis of Poly(o-phenylenediamine) Hollow Spheres and Nanofibers Using Different Oxidizing Agents
Preparation of Zinc Gluconate Nanostructures with Different Shapes by Lamellar Liquid Crystal Templa
Microstructure and Lubrication Properties of Lamellar Liquid Crystal in Brij30/[Bmim]PF6/H2O System
Acid–base Equilibrium of Puerarin in CTAB Micelles
Fabrication of PbS Microstructures with Different Shapes in Aqueous Solutions of Amphiphilic Tribloc
Interaction between Casein and Sodium Dodecyl Sulfate
Microenvironment Effect on the Location Distribution of Phenothiazine in Cetyltrimethylammonium Brom
The Iinteraction between Hemoglobin and Two Surfactants with Different Charges
The Self-organization Properties of n-dodecylammoniumα-glutamate/n-C5H11OH/water System
Fabrication of Polymer Hollow Nanospheres by a Swelling–Evaporation Strategy
Decompaction of Cationic Gemini Surfactant-Induced DNA Condensates by β-Cyclodextrin or Anionic Surf
Micellization-Induced Conformational Change of a Chiral Proline Surfactant
Effect of Surfactant Structure on the Stability of Carbon Nanotubes in Aqueous Solution
pH-dependent Structures and Properties of Casein Micelles
Interaction between Casein and the Oppositely Charged Surfactant
Synthesis of Polymer Hollow Spheres with Holes in Their Surfaces
Polyaniline Hierarchical Structures Synthesized in Aqueous Solution: Micromats of Nanofibers
Combined Antioxidant Effects of Rutin and Vitamin C in Triton X-100 micelles
The Effect of Sodium Dodecyl Sulfate on the Conformation of Bovine Serum Albumin
Morphological and structural modulation of PbWO4 crystals directed by dextrans
Aggregation Behavior of a Tetrameric Cationic surfactant in Aqueous Solution
Molecular Conformation-Controlled Vesicle/Micelle Transition of Cationic Trimeric Surfactants in Aqu
Effects of Inorganic and Organic Salts on Aggregation Behavior of Cationic Gemini Surfactants
Highly Fluorescent Aggregates Modulated by Surfactant Structure and Concentration
Self-assembly of Peptide-Amphiphile C12-Aβ(11-17) into Nanofibrils
Aggregation properties of zwitterionic surfactants with different ionic headgroups, hydrophobic chai
Dilute Anionic Surfactant Solution Route to Polyaniline Rectangular Sub-microtubes as a Novel Nanost
Polymer-assisted crystallization and optical properties of uniform microrods of the organic dye Suda
Polyaniline Fan-like Architectures of Rectangular Sub-Microtubes Synthesized in Dilute Inorganic Aci
Controlled Synthesis of Pyramid-Aggregated Sphere-like Cadmium Sulfide in the Presence of a Polymer
Effect of Surfactant Structure on Catalysis of Microemulsion for Photoisomerization of Trans-stilben
Studies on Molecular Interactions between Puerarin and PC Liposomes
Transfer and Distribution of L-tryptophan between W/O and O/W,and between W/O and Bicontinuous Micro
Structure of adsorbed layers of nitrophenoxy-tailed quaternary ammonium surfactants at the air/water
Aggregation Behavior of Nitrophenoxy-Tailed Quaternary Ammonium Surfactants
Fabrication of Polyaniline with Hierarchical Structures in Alkaline Solution
Comparative Studies on Adsorption Behavior of Thionine on Gold Nanoparticles with Different Sizes
Nanostructure-Based Leaf-like Polyaniline in the Presence of an Amphiphilic Triblock Copolymer
Polymer-controlled synthesis of silver nanobelts and hierarchical nanocolumns
Abnormal Interfacial Tension Behavior of Alkanediyl-αω-bis(dodecyldimethylammonium bromide) Gemini S
Synthesis of hollow PbS Nanospheres in Pluronic F127/cyclohexane/H2O Microemulsions
Aggregation properties of cationic gemini surfactants with dihydroxyethylamino headgroups in aqueous
Fabrication of Polymer Hollow Nanospheres by a Swelling–Evaporation Strategy
Modification of MnO2 Nanoparticles with Rutin Synthesized by Triton X-100 Aggregations’ Template
Fabrication of Novel CdIn2S4 Hollow Spheres via a Facile Hydrothermal Process
Growth of Dendritic Silver Crystals in CTAB/SDBS Mixed-Surfactant Solutions
Shape evolution of Cu2S nanostructures in Triton X-100/cyclohexane/water reverse micelles
Studies on the Antioxidant Effect of Rutin in the Microenvironment of Cationic Micelles
Micellization of Surfactin and Its Effect on the Aggregate Conformation of Amyloid β(1-40)
Highly-Ordered Selective Self-Assembly of a Trimeric Cationic Surfactant on a Mica Surface
PEG-Induced Lamellar-to-Isotropic Phase Transition in the System of TX-100/n-C8H17OH/H2O
A Simple One-Step Chemical Route to Gold/Polymer Core/Shell Composites and Polymer Hollow Spheres
Ionic Liquid Induced Transition from Wormlike to Rod or Spherical Micelles in Mixed Nonionic Surfact
Br?-Induced Facile Fabrication of Spongelike Gold/Amino Acid Nanocomposites and Their Applications i
Enhancement of Wormlike Micellar Structure Induced by O-Carboxymethylchitosan with or without Hydrop
Facile Fabrication of Pomponlike Microarchitectures of Lanthanum Molybdate via an Ultrasound Route
Constant Vapour Pressure Evaporation from a Fragrance Emulsion—Effect of Surfactant Content in the L
Stability versus Phase Ratios of Geranyl Acetate three-phase Emulsions
Initial Inter-phase Transport of Compounds in a Model Emulsion System
Nanoporous anatase TiO2 mesocrystals: additive-free synthesis, remarkable crystalline-phase stabilit
Facile fabrication of two-dimensionally ordered macroporous silver thin films and their application
Porous gold nanobelts templated by metal-surfactant complex nanobelts
Facile fabrication of honeycomb-patterned thin films of amorphous calcium carbonate and mosaic calci
Colloidal-crystal-assisted patterning of crystalline materials
Interaction of Methemoglobin with GDA/n-C5H11OH/water Assemblies
The Photostabilization of Hemoglobin in Triton X-100 Aqueous Solution and Triton X-100/n-C5H11OH/H2O
Transfer and Distribution of Methylene Blue through w/o-o/w and w/o-bicontinuous Interface
Novel Reactive Template Method to Synthesize Gold Nanoparticles with Controllable Size and Morpholog
Effect of Hydrotropic Salt on the Assembly Transitions and Rheological Responses of Cationic Gemini
Colloidal chemical approaches to inorganic micro- and nanostructures with controlled morphologies an
Solution-phase synthesis of one-dimensional semiconductor nanostructures
Synthesis and Properties of Novel Gemini Surfactant with Short Spacer
离子液体[BMim]BF4对SDS水溶液表面活性和聚集能力的促进
基于胱氨酸的Gemini型表面活性剂的合成及其性质
具有短连接基团的新型Gemini表面活性剂的合成与性质
葛根素与卵磷脂囊泡的相互作用
会议论文
Biotemplated synthesis of gold nanoparticle-bacteria cellulose nanofiber nanocomposites and their ap
A Quantitative Structure-Property Relationship Study of the Critical Micelle Concentration of Ionic
Polymer-directed synthesis of inorganic materials with controlled morphologies and architectures
Facile Synthesis and 1D assembly of Cyclodextrin-Capped Gold Nanoparticles and Their Applications in
Topotactic Transformation of Single-Crystalline Precursor Discs into Disc-Like Bi2S3 Nanorod Network
First Example of Polymer Stablized Gold Nanoparticles for Suzuki-Miyaura Cross-Coupling Reaction
Tunable assemblies based on metal coordination polymers and oppositely charged block polyelectrolyte
含药物端基非离子表面活性剂的合成及在介孔材料合成中的应用
水中苯胺氧化聚合制备聚苯胺多级结构
Bola型表面活性剂的及其复配体系的聚集行为
甘油诱导的双水相体系相行为及聚集行为的转变
嵌段共聚物的亲疏链长度对亲水改性布洛芬/嵌段共聚物复合聚集体结构的影响
Bio-Inspired Fabrication of Patterned, Crystalline Calcium Carbonate via Colloidal Crystal Templates
Modulation of the Interaction between Ionic Surfactant and BSA bythe Addition of Cyclodextrins
阴离子表面活性剂稀溶液方法制备聚苯胺矩形亚微米管
F127/TX-100复合物的生成及结构转变
纳米孔氧化锌中空球的微波法合成
Effect of Surfactants on Aggregation Behavior of Alzheimer Amyloid β(1-40) Peptide
含对硝基苯醚基团的阳离子表面活性剂在水溶液中的聚集行为
Templating Approaches towards Inorganic Nanostructures with Controlled Morphologies and Patterns
表面活性剂的结构对碳纳米管在水相中稳定性的影响
Modulation of Aβ(1-40) Fibrillogenesis by Cationic Gemini Surfactant
表面活性剂结构与微乳液对1，2－二苯乙烯顺反光异构反应的催化作用
肽两亲分子C12-Aβ(11-17)在水溶液中的自组装
聚邻苯二胺空心和实心球对于铅离子吸附性能研究
寡聚表面活性剂在水溶液中特殊的聚集行为研究
共沉淀机理合成表面修饰介孔材料及其在药物释放中的应用
表面活性素的胶束化以及对amyloid β(1-40)聚集行为的影响
盐对阳离子Gemini表面活性剂溶液聚集行为的影响
TritonX-100/n-C10H21OH/H2O层状液晶中聚苯胺润滑作用
微量热法和荧光法研究明胶与十二烷基硫酸钠的相互作用
两亲性壳聚糖衍生物聚集体与牛血清蛋白的相互作用
金纳米粒子-细菌纤维素纳米纤维复合结构的合成及其生物传感应用
聚苯胺衍生物纳米纤维的空心化：溶胀-蒸发法
表面活性剂对硫堇与核酸相互作用的影响
一步溶液合成法制备导电聚合物/Au复合纳米材料
抗菌性药物在仿生膜中的助溶－增溶作用
TX-100/n-C8H17/PEG(aq)体系层状液晶的微结构与相行为
GDA/n-C5H11OH/Water体系自组装聚集行为与血红蛋白的相互作用
声化学方法制备绒球状微米La2(MoO4)3
酪蛋白溶液中纳米金的制备
制备形貌可控的聚合物基金纳米粒子的新方法：活性模板法
Ca2+离子对新型两亲壳聚糖衍生物聚集形态的影响
α-环糊精对表面活性剂与牛血清白蛋白相互作用的影响
管状聚苯胺吸附汞离子的研究
两亲三嵌段共聚物/离子液体溶液的流变行为研究
Morphology-controlled synthesis of one-dimensional nanostructures in micellar systems
Colloidal Chemical Routes to Morphology-Controlled Inorganic Nanostructures
Colloidal crystal-assisted fabrication of inorganic nanostructures with controlled architectures
Constant Vapor Pressure Evaporation from a Fragrance Emulsion
Facile Fabrication of Pomponlike Microarchitectures of Lanthanum Molybdate via a Surfactant-assiste
离子液体与DNA相互作用的缔合特性和分子机理
金属诱导的超分子螺旋
Morphology-Controlled Synthesis of Inorganic Nanostructures Based on Soft and Hard Templates
Gemini表面活性剂与聚合物的液液相分离
离子液体基表面活性剂OOIM-Br与两亲嵌段共聚物F127的相互作用研究
Aggregation Behavior of Cationic Gemini Surfactants with Functional Groups
Micellization of Surfactin and Its Interaction with Amyloid β(1-40)
利用Ag2C2O4纳米纤维模板合成Ag2S, Ag2Se和Ag纳米纤维
SDS和Tween 80 混合体系的结构特征
纳米氧化钕的制备
海胆牙齿的生物矿化研究
酪蛋白胶束与纳米金胶之间相互作用的研究
溶剂热法调控NiS晶体的制备
离子液体与囊泡的缔合行为
磺基水杨酸对聚苯胺形貌的调控
电化学方法对铜纳米结构的调控
Gemini表面活性剂胶束对amyloid纤维的解聚作用
基于胶体晶体模板的新型纳米结构的溶液相合成
实心球前体模板转化合成Bi2E3 (E=S, Se, Te)系列核壳结构
胶束对桑色素与人血清蛋白相互作用的影响
分子有序组合体与血红蛋白的相互作用
胞外多聚物作用下羟基氧化铁的生物矿化研究
无机钠盐对有机小分子与酪蛋白胶束结合特性的影响
空心液滴模板法制备聚苯胺衍生物空心球
疏水取代的羧甲基壳聚糖对CTAB蠕虫状胶束结构的影响
胶体化学法合成形貌可控的无机纳米结构
单晶圆盘前体转化法合成圆盘状Bi2S3纳米网格结构
表面活性剂与芹菜素对BSA表面疏水的影响
以介孔氧化硅一维纳米结构为牺牲模板合成氧化锡纳米管
胶体球平版印刷法构筑图案化的氧化锌纳米结构阵列
胶体晶体模板法生长三维有序大孔碳酸钙单晶
嵌段共聚物（P123）在乙二醇和PEG200中的凝胶行为
新型四聚表面活性剂PATC在水溶液中聚集行为研究
苯甲酸钠对阳离子Gemini表面活性剂溶液聚集行为的影响
Bio-Inspired Fabrication of Nanopatterned CaCO3 Crystals via Colloidal Crystal Templates
组氨酸基bola型表面活性剂（H2D）与普通表面活性剂十二烷基三甲基溴化铵（DTAB）混合体系中纳米Cu的制备
Aggregation Behavior of Gemini Surfactants and Their Special Interaction with Biomacromolecules in A
Polymer-Induced Lamellar-to-Isotropic Phase Transition in the System of TX-100/n-C8H17OH/H2O
1H NMR Investigation on Micellization-Induced Conformational Change of Chiral Amino Acid Surfactant
Synthesis of Tailored Nanostructures by Using Reactive Templates and Colloidal Crystal Templates
π-π堆积作用驱动的不对称Bola两亲分子的平行排列
(－环糊精对蛋白－表面活性剂相互作用的调控
新颖的三聚阳离子表面活性剂DDAB的物化性质研究
温度对不同链长的Gemini表面活性剂与牛血清蛋白相互作用的影响
阳离子型Gemini表面活性剂对Aβ(1-40)纤维化的调控
嵌段共聚物诱导下的CdS纳米结构的控制合成
表面活性剂/H2O体系中血红蛋白的光物理和光化学性质
十二烷基硫酸钠/明胶体系的气－液界面吸附行为的研究
CTAB体系中叶绿素铜钠的聚集行为
等温滴定微量热法研究金属阳离子在金纳米粒子表面的吸附行为
聚乙二醇与亲水改性布洛芬的相互作用
Application of Amphiphilic Self-assemblies in the Biomedical Field
Self-assemblies based on metal coordination polymers and oppositely charged block polyelectrolytes
溶液中两亲分子有序组合体的构筑(大会邀请报告)
溶液中两亲分子有序组合体的构筑与应用
基于金属配位高分子和异电性双亲水嵌段共聚电解质的可控分子有序组合体
丹磺酰标记表面活性剂的合成及其在分子有序组合体中的应用
Gemini表面活性剂头基的碳氢链对体系中聚集体的影响
Gemini表面活性剂溶液表面性质和聚集行为的氧化还原调控
基于Gemini型表面活性剂的疏水链间相互作用调控肉桂酸的光致二聚
一类具有pH响应的粘弹性流体
基于添加剂方法的温度和pH双响应的囊泡
基于弱相互作用构筑的有序双螺旋结构
组氨酸型两亲分子纳米纤维模板合成氧化物纳米管
Beta-环糊精在正负表面活性剂体系中的特殊作用
一维有序的螺旋纳米结构：从有机自组装到无机材料
金属离子驱动的一维纳米有序组合体
层层组装促进金属配位超分子形成的研究
阳离子表面活性剂体系中的pH敏感微观结构的转化和相行为
疏水链中含有对硝基苯醚基团的阳离子Gemini表面活性剂在水溶液中胶束化的热力学研究
Transformation of surfactant aggregates in solution
温度对不同链长的Gemini型和CnTAB型表面活性剂与牛血清蛋白相互作用的影响
Morphology-controlled mineralization of calcite single crystals
Controlled Synthesis of Tailored Nanostructures by Templating Approaches
Colloidal crystal-assisted fabrication of patterned nanostructures
Colloidal crystal-assisted fabrication and assembly of patterned nanostructures
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