目的探索偏侧咀嚼对紧咬牙运动时脑功能活动的影响。方法选取左、右侧偏侧咀嚼患者各7例,在紧咬牙运动时采集全脑血氧水平依赖对比的功能性磁共振成像(functional magnetic resonance imaging,fMRI)扫描数据。结果7例左侧偏侧咀嚼患者中有4例出现海马旁回的激活,而右侧偏侧咀嚼患者均未见海马旁回的激活。结论发现了左侧偏侧咀嚼患者紧咬牙运动可激活与人类学习记忆能力有重要关系的海马旁回的现象。
Objective To explore effects of chewing-side preference (CSP) on cerebral cortical response during clenching task with functional magnetic resonance imaging (fMRI). Methods Seven patients with left CSP and 7 patients with right CSP were selected to perform the maximum voluntary clenching in intercuspal position, and block designed blood oxygenation level-dependent(BOLD) fMRI scan covering the whole brain was carried out. Results There was activation in the parahippocampal gyrus in the four patients among seven with left CSP. But there was no activation in the parahippocampal gyrus among the patients with right CSP. Conclusions This research shows that the parahippocampal gyrus, which is associated with human memory and study, is activated during clenching task in the patients with left CSP.