目的:优选制备当归挥发油β-环糊精包合物的最佳方法。方法:采用单因素筛选及正交实验相结合,以包合率为指标,优选最佳包合工艺。结果:最佳包合方法为饱和水溶液法,包合条件为当归挥发油与β-环糊精的比例为1∶8,β-环糊精与水的比例为1∶6,搅拌时间4 h。结论:优选的包合工艺操作简便、工艺稳定、挥发油包合率较高。
Objective:To optimize the preparation process of β-cyclodextrin(β-CD) inclusion compound of Angelica oil.Methods: Single factor experiment and orthogonal design were used together,oil inclusion rate was used as an index,then chose the best preparation technology.Results: The optimal method was saturated solution method.The preparation condition for inclusion was as follows: the ratio of Angelica oil to β-CD was(1∶ 8),the ratio of β-CD to water was(1∶ 6) and the stirring time was 4 h.Conclusion: The preparation procedure of inclusion volatile oil is simple,stable,reliable and high inclusion rate.