中文摘要：

目的：观察佛手散不同乙醇浓度提取液对血虚动物模型的补血作用,探讨其补血作用特点。方法：应用乙酰苯肼与环磷酰胺复合法复制血虚小鼠模型。造模过程中称体重,造模结束后于小鼠眼底后静脉丛采血测血常规;取小鼠胸腺、脾脏、肝脏称取湿重,并计算脏器指数;用比色法测肝匀浆中总抗氧化能力（T-AOC）,黄嘌呤氧化酶法测定超氧化物歧化酶（SOD）活性;最后采用权重系数法将以上指标整合为单指标,以探讨佛手散不同乙醇浓度提取液的总补血效应变化规律。结果：佛手散不同乙醇浓度提取液对模型小鼠降低的体重有升高作用;对降低的白细胞数、红细胞数、血小板数、血压积有升高作用,对降低的胸腺指数和脾脏指数有升高作用,对升高的肝脏指数有降低作用,对降低的肝脏T-AOC能力和SOD活性有升高作用;佛手散不同乙醇浓度提取液的总补血效应值大小顺序为：40%〉30%〉20%〉50%〉15%〉70%〉10%〉5%〉95%〉0%。结论：佛手散不同乙醇浓度提取液对血虚小鼠均有一定的补血作用,其中以40%醇浓度提取佛手散的补血效果最优。

英文摘要：

AIM： To study the enriching blood effect of Fo-shou-san（FSS） extracted with different ethanol concentration on blood deficiency animal and approach the action characteristics of enriching blood. METHODS： The blood deficient mice model was induced by injection of phenylhydrazine and cyclophosphamide.The body weight of mice was recorded during the induction of model.After the model was established,blood was collected from the retroorbital plexus,and the blood routine,thymus index,spleen index,and liver index were determined.Total antioxidant capacity（T-AOC） and superoxide dismutase（SOD） in liver were detected by colorimetric method and xanthine oxidase method,respectively.Those indexes were calculated to a single index by the weight coefficient method for exploring the total enriching blood effect.RESULTS：FSS extracted with different ethanol concentration could increase the number of white blood cell,red blood cell,platelet and hematocrit in model mice;increase weight,thymus index,and spleen index of model mice,while decrease liver index of model mice;and increase the activity of T-AOC and SOD in liver.The order of FSS extracted with different concentration of ethanol on total enriching blood effect was： 40%30%20%50%15%70%10%5%95%0%.CONCLUSION： FSS extracted with different ethanol concentration has the activity of enriching blood on blood deficiency model mice,and 40% ethanol extraction showed the best effect.