目的 描述中国慢性病前瞻性研究(CKB)队列的10个地区人群中高血压的患病、知晓、治疗和控制现状及其地区差异。方法 CKB项目于2004-2008年在10个项目地区募集512891名30-79岁队列成员并完成基线调查。本研究利用CKB项目的基线信息,比较对年龄和/或性别进行调整后高血压患病率、知晓率、治疗率及其控制情况的地区差异。结果 10个项目地区中,高血压患者共180621人(35.2%),其中浙江项目地区患病率最高(44.4%),海口项目地区患病率最低(22.0%)。农村地区人群患病率(35.1%)高于城市(32.1%),差异有统计学意义(P〈0.001)。在高血压人群中,知晓率为33.1%(59703/180621),治疗率为36.1%(65172/180621),控制率为12.4%(22329/180621),服用降压药物的人群中控制率为30.5%(19884/65172),其中苏州项目地区的男性控制率(17.4%)和服药控制率(39.1%)高于其他地区,柳州项目地区的女性控制率(23.5%)和服药控制率(42.6%)高于其他地区。结论 CKB项目10个地区人群中高血压患病率较高,知晓率、治疗率和控制率偏低,研究人群的高血压患病、知晓、治疗和控制情况存在明显地区差异。
Objective To describe the status of prevalence, awareness, treatment, and control of hypertension among half a million adults in 10 regions under the China Kadoorie Biobank(CKB) cohort. Methods The baseline survey of CKB was performed in 10 areas across China during 2004-2008, included 512891 adults aged from 30 to 79 years. Regional differences of prevalence, awareness, treatment and control of hypertension were compared after adjustment for age and/or sex. Results The overall prevalence of hypertension from the CKB was 35.2%(180612/512891), with the highest as 44.4% in Zhejiang and the lowest as 22.0% in Haikou. Prevalence in the rural areas(35.1%) was higher than that in the urban areas(32.1%), with statistical significance(P〈0.001). Among all the participants with hypertension, 59703(33.1%) were aware of hypertension, 65172(36.1%) were receiving anti-hypertension treatment and 22329(12.4%) were under controll. However, only a small part of those receiving treatment were under controll(30.5%, 19884/65172) in this study. The control of hypertension and of those receiving treatment were higher in Suzhou for males(17.4%, 39.1%), while were higher in Liuzhou for females(23.5%, 42.6%) than those in other regions. Conclusions Participants under the CKB presented relatively high prevalence of hypertension, but lower rates on awareness, treatment and control of hypertension. Distribution of awareness, treatment, and control of hypertension varied greatly among the ten areas, under the CKB.