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中文摘要：
采用改进的Atherton-Todd反应对染料木素进行磷酰化结构改造，得到了4种新的磷酰化产物，并通过ESI-MS，NNR进行了结构确认，结果发现磷酰化试剂对染料木素羟基的磷酰化具有较好的选择性，反应主要发生在染料木素7位羟基；进一步利用ESI质谱技术，对4种磷酰化染料木素与大分子溶菌酶的弱相互作用进行测定，显示所有的磷酰化产物均与溶菌酶形成非共价复合物。
英文摘要：
A series of genistein＇ s phosphates were synthesized through a simplified Atherton-Todd reaction and the structures of the phosphates were determined by electrospray ionization mass spectrometry （ESI-MS） and NMR. In case of monophosporyl derivatives, NMR spectra show that substitutions occur at the 7-position of genistein but not at its 4＇ and 5-position. Moreover, the non-covalent complexes of lysozyme with the four new genistein phosphates were detected by ESI-MS.
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