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中文摘要：
建立了快速检测去羟肌苷的化学发光方法。在HNO3介质中,去羟肌苷对KMnO4-Na2SO3化学发光体系有较强的抑制作用,且抑制的程度与去羟肌苷的质量浓度在一定范围内呈良好的线性关系,据此可以测定去羟肌苷含量。方法的线性范围为4.0×10^-7-1.0×10^-4g/mL,检出限为9.6×10^-8g/mL。对8.0×10^-5g/mL去羟肌苷测定的相对标准偏差为2.0%（n=11）。方法适用于胶囊中去羟肌苷的含量测定。
英文摘要：
To develop a method for the determination of didanosine by chemiluminescence （CL） Didanosine can greatly inhibit the intensity of the chemiluminescence reaction between KMnO4 and sulphite in a nitric acid medium, and there was a good linear relationship between the inhibition and the concentration of clidanosine. Based on this phenomenon, didanosine was determined. The linear range of didanosine was 4.0×10^-7-1.0×10^-4g/mL and the limit of detection was 9.6 × 10^-8 g/mL. The relative standard deviation （n = 11） was 2.0% for 8.0 × 10^-5 g/mL didanosine. The method could be applied to the determination of didanosine in capsule due to its simplicity, high efficiency and high sensitivity.
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