中文摘要：

在 386 个动脉瘤的 subarachnoid 出血病人的一个中国 population.MethodsA 总数在动脉瘤的 subarachnoid 出血以后探索在浆液 gamma-glutamyl transferase 层次和功能的结果之间的潜在的协会的 ObjectiveWe 目的从 2007 年 9 月在学习被包括到 2015 年 2 月。基线浆液 gamma-glutamyl transferase 层次和 6 月的后续功能的结果被决定。差的结果被定义为 3 的一个修改评价规模分数。multivariable 在动脉瘤的 subarachnoid hemorrhage.ResultsThe 与 gamma-glutamyl transferase 层次调整了病人的差的结果率以后，逻辑模型被用来分析在浆液 gamma-glutamyl transferase 和临床的结果之间的关系 < 30 U/L， 30-50 U/L 和 50 U/L 是 16.7% ， 19.6% ，和 34.4% ，分别地(P < 0.01 ) 。年龄性和 multivariable 调整了把优秀的组(50 U/L ) 与最低的组作比较的差的预后的机会比率(95% 信心间隔)(< 30 U/L ) 是 5.76 (2.74-12.13 ) ， 6.64 (2.05-21.52 ) ，并且 6.36 (1.92-21.02 ) 。一个重要线性趋势在 gamma-glutamyl transferase 水平和动脉瘤的 subarachnoid 出血预后之间存在。这个协会也与更高的 gamma-glutamyl transferase 层次在 nondrinkers.ConclusionPatients 之中被观察是更可能的有差的预后。浆液 gamma-glutamyl transferase 能被认为是在动脉瘤的 subarachnoid 出血以后的功能的结果的一个独立预言者。

英文摘要：

Objective We aim to explore the potential association between serum gamma-glutamyl transferase levels and functional outcome after aneurysmal subarachnoid hemorrhage in a Chinese population. Methods A total of 386 aneurysmal subarachnoid hemorrhage patients were included in the study from September 2007 to February 2015. Baseline serum gamma-glutamyl transferase levels and 6-month follow-up functional outcomes were determined. A poor outcome was defined as a modified ranking scale score of ≥ 3. The multivariable logistic model was used to analyze the relationship between serum gamma-glutamyl transferase and clinical outcomes after aneurysmal subarachnoid hemorrhage. Results The adjusted poor outcome rates of patients with gamma-glutamyl transferase levels of 〈 30 U/L, 30-50 U/L and ≥ 50 U/L were 16.7%, 19.6%, and 34.4%, respectively （P 〈 0.01）. The age-sex and multivariable adjusted odds ratios （95% confidence intervals） of poor prognosis comparing the top group （≥ 50 U/L） with the lowest group （〈 30 U/L） were 5.76 （2.74-12.13）, 6.64 （2.05-21.52）, and 6.36 （1.92-21.02）. A significant linear trend existed between gamma-glutamyl transferase level and aneurysmal subarachnoid hemorrhage prognosis. This association was also observed among nondrinkers. Conclusion Patients with higher gamma-glutamyl transferase levels were more likely to have a poor prognosis. Serum gamma-glutamyl transferase can be considered to be an independent predictor of functional outcomes after aneurysmal subarachnoid hemorrhage.