采用同步辐射类同轴相位衬度成像技术.对不同状态下的小鼠肝脏样本成像.并对成像结果进行三维重建。实验是在上海光源X射线成像及生物医学应用光束站线BL13W1上完成的.成像样本为正常小鼠肝脏。实验结果表明.干燥的肝脏样本在相位衬度成像实验中成像效果最好。通过滤波反投影算法,成功得到样本的二维断层图像:使用表面绘制方法.重构三维血管图像既能显示大血管.又能显示7级以上的细小分支。研究证明,采用同步辐射类同轴成像技术能够显示小鼠肝脏组织的内部细节,有望成为观察肝脏细节的手段。
The liver sample of mouse under different conditions is investigated in this paper, and the three-dimensional vessel system of mouse liver is established. The experiments were performed at X-ray imaging and biomedical application beamline (BL13W1) of Shanghai Synchrotron Radiation Facility (SSRF). The results show that dry liver sample has the best imaging quality. By the approach of filter back projection (FBP), the tomography images are obtained. The vessel tree is reconstructed by the use of surface rendering. It reveals that in-line phase contrast imaging technique has the ability to visualize structures inside mouse liver and has the potential to be used in liver imaging in the future.