中文摘要：

乳酸杆菌在发酵工业有着极其重要的作用,然而在乳酸杆菌高密度培养中却很难达到高的活菌数（一般活菌数在109 cfu/m L）,这与其培养及生长过程中所处的环境有关。由于乳酸杆菌在高密度培养过程中往往通过流加碱液来消除酸的反馈抑制,而随之便会产生高渗应激问题,因此提出了相容性溶质的概念,在此就乳酸杆菌高渗应激反应及相容性溶质的作用等进行了简单的阐述和讨论。

英文摘要：

Lactobacillus has a very important role in the fermentation industry. However, the concentration of live bacteria is difficult to achieve a high level during the Lactobacillus high-density culture （the concentration is usually 109 cfu/mL）. The concentration of live bacteria is related to the environment of bacteria growth. In order to eliminate inhibition of acid adding lye into the medium is necessary during the Lactobacillus high-density culture. But that will result in hypertonic stress of bacteria. Therefor, the concept of compatible solutes is put forward. The hypertonic stress response of Lactobacillus and the role of compatible solutes is elaborated and discussed.