利用经过无规聚合物P(MMA-co-MPS)修饰的羟基磷灰石(HA),与聚丙烯酸甲酯(PMMA)混合,制备了HA/PMMA复合骨水泥。研究了HA含量、HA的修饰程度对复合骨水泥压缩强度、弯曲强度和弯曲模量等力学性能的影响。MTT实验表明HA/PMMA复合骨水泥对细胞无毒性。
Hydroxyapatite(HA) particles modified with random copolymer P(MMA-co-MPS) were mixed with Poly(methylmethacrylate)(PMMA) to form the composite bone cement.The effects of HA particles content and the degree of HA modification on compressive strength,flexural strength and flexural modulus of bone cement were studied.The MTT assay showed that the HA/PMMA composite bone cements were non-toxic to cells.