中文摘要：

壳聚糖是天然多糖中唯一的碱性多糖,具有降脂、降胆固醇、提高免疫力、抗肿瘤等多种重要的生理功效。主要介绍壳聚糖在小鼠体内的分布和排泄情况的研究进展和壳聚糖的代谢途径,对其进一步药代动力学的研究具有指导意义。

英文摘要：

Chitosan was the only alkaline polysaccharide in nature,which had various important physiological functions,such as reducing fat and cholesterol,enhancing immunity,antitumor,etc.The distribution and excretion of chitosan were investigated,and metabolic pathways of chitosan were pointed out,which was significance for the further study of pharmacokinetic.