中文摘要：

目的 探讨64层螺旋CT测量肾积水体积用于评估梗阻性肾积水患者肾功能的价值.方法 选取在本院3 d内同时行单光子发射计算机体层成像（SPECT）肾动态显像及64层螺旋CT平扫的梗阻性肾积水患者共176例.根据SPECT测得的肾小球滤过率（GFR）将其分为肾功能正常组、肾功能轻度受损组、肾功能中度受损组及肾功能重度受损组.同时利用CT三维重建技术测量各组患者的肾积水体积大小,然后对比各组间肾积水体积的差异,并分析肾积水体积与GFR的相关性.结果 4组患者肾积水体积分别为（31.47±3.81） cm3、（83.43±7.81） cm3、（208.53±15.47） cm3 及（577.31±61.32） cm3 ,差异有统计学意义（P〈0.01）;组间两两比较除肾功能正常组与肾功能轻度受损组外,其余各组间差异均有统计学意义（P〈0.01）;肾积水体积与肾脏GFR具有良好的相关性（r=-0.614）.结论 64层螺旋CT测得的肾积水体积与SPECT测得的GFR有较好的相关性,能在一定程度上反映肾积水患者的肾脏功能.

英文摘要：

Objective To explore the value of hydronephrosis volume measured by 64 slice CT scan, evaluating renal function in patients with obstructive hydronephrosis.Methods The patients performed with both single photon emission computed tomography（SPECT） renal dynamic imaging and 64 slice CT scan in three days were chosen, 176 cases included finally.The images of renal dynamic imaging were divided into normal renal function group, mild renal impairment group, moderate renal impairment group and severe renal impairment group according to glomerular filtration rate （GFR） measured by SPECT.At the same time, CT three-dimensional reconstruction technique has been used to measure the volume of hydronephrosis, compare the differences of hydronephrosis volume among these groups, and future analyze the correlation of hydronephrosis volume with renal GFR value.Results The hydronephrosis volume of the four groups were respectively （31.47±3.81） cm3,（83.43±7.81） cm3,（208.53±15.47） cm3 and （577.31±61.32） cm3.There was statistical significance among these groups （P〈0.01）,except between normal renal function group and mild renal impairment group.The volume of hydronephrosis showed positive correlations with renal GFR （r=-0.614）.Conclusion The volume of hydronephrosis measured by 64 slice CT has positive correlation with GFR measured by SPECT, which could reflect renal function to some extent.