目的评价中文版可重复神经心理状态测验(repeatable battery for the assessment of neuro-psychological status,RBANS)在精神分裂症患者人群应用的信度和效度。方法筛查100名精神分裂症患者,其中98名患者完成中文版RBANS问卷、世界卫生组织认知功能评价成套神经心理测验(WHO-BCAI)和Stroop字色干扰测验,同时使用阳性阴性综合征量表(PANSS)和临床疗效总评(CGI)评价患者病情的严重程度。其中43例患者间隔一月后复测RBANS。对获取的数据进行相关分析等。结果RBANS总分与RBANS5个因子分的相关系数具有统计学意义(r=0.475-0.778,P〈0.001)。RBANS总分重测信度ICC为0.877,5个因子ICC从0.453-0.875。除了RBANS的视觉空间结构与WHO—BCAI的延迟回忆,RBANS的语言与WHO—BCAI的视觉辨认功能、空间结构相关系数未达到统计学意义外,RBANS总分、各因子分与WHO-BCAI及Stroop字色干扰测验的相关系数具有统计学意义。结论中文版RBANS在精神分裂症患者中应用具有较好的信度和效度,可作为精神分裂症患者认知功能水平的筛查工具。
Objective: To explore the reliability and validity of Chinese version of repeatable battery assessment of neuropsychological status (RBANS) in schizophrenic patients. Methods: Ninety - eight of 100 schizophrenic inpatients screened completed evaluation with RBANS, WHO neuropsychological battery of cognitive assessment instruments (WHO-BCAI) and Stroop test. Forty-three of them were re-evaluated with RBANS after more than one month. Severity of illness was measured by positive and negative syndrome scale (PANSS) and clinical global impression (CGI). Correlation analysis was conducted on data collected. Results:The total score of RBANS demonstrated highly significant correlation to 5 index scores (r =0.475-0.778 ,P 〈0.001), and its test- retest reliability correlation was 0.877. Conclusion:The Chinese version RBANS had relatively good reliability and validity and may be a useful screening instrument for cognitive function in schizophrenic patients.